DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Eb1 and EB1a

DIOPT Version :9

Sequence 1:	NP_724495.2	Gene:	Eb1 / 35584	FlyBaseID:	FBgn0027066	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_190353.3	Gene:	EB1a / 823923	AraportID:	AT3G47690	Length:	276	Species:	Arabidopsis thaliana

Alignment Length:	309	Identity:	103/309 - (33%)
Similarity:	156/309 - (50%)	Gaps:	61/309 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVNVYSTNVTSENLSRHDMLAWVNDCLQSQFSKIEELCTGAAYCQFMDMLFPNSVPVKRVKFRT 65
            ||.|:...: ::..:.|:::|.|:||.|....|::||..:||..||.:||.||..||:.:|.|..
plant     1 MATNIGMMD-SAYFVGRNEILTWINDRLHLNLSRVEEAASGAVQCQMLDMTFPGVVPMHKVNFDA 64

  Fly    66 NLEHEYIQNFKILQAGFKKMSVDKIIPVDKLIKGRFQDNFEFLQWFKKFFDANYDG---REYDPV 127
            ..|::.|||:|:||..|.|:.:.|.:.:::|:|||..||.|||||.|:|.|:...|   ..|:||
plant    65 KNEYDMIQNYKVLQDVFNKLKITKPLEINRLVKGRPLDNLEFLQWLKRFCDSINGGIMNENYNPV 129

  Fly   128 AQRGGVKLGNGNGHGSNGGSGVGSSNNDLHLMHRRPLQAPASGGRMPARVIASTAVSKVLPRTNN 192
            .:|.    .||......|                                  |..:.|.|...||
plant   130 ERRS----RNGKERSVKG----------------------------------SNKIPKSLQTNNN 156

  Fly   193 AAPASRINACANSTGTVKKNDVSNSVNNQQIEEMSNQVMDMRINLEGLEKERDFYFSKLRDIEIL 257
            ..|.:     ::|.| :.|.....|....:::.:|.:::|::|:.:.||||||||||||||:|||
plant   157 HPPPN-----SSSVG-LSKASGPKSAKAAEVQALSKELVDLKISTDLLEKERDFYFSKLRDVEIL 215

  Fly   258 CQ--EADDAEAHPIIQKILDILYATEDGFAPPDDAPP--------EDEE 296
            ||  |.||.   ||:..:..|||||:...:..:||..        ||:|
plant   216 CQTPELDDL---PIVVAVKKILYATDANESALEDAQEYLNQSLGVEDDE 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eb1	NP_724495.2	BIM1	16..293	CDD:227542	97/289 (34%)
		CH	16..114	CDD:278723	43/97 (44%)
		EB1	241..279	CDD:281288	25/39 (64%)
EB1a	NP_190353.3	BIM1	8..270	CDD:227542	100/302 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2253
eggNOG	1	0.900	-	-		E1_COG5217
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I1604
OMA	1	1.010	-	-		QHG56844
OrthoDB	1	1.010	-	-		D1237523at2759
OrthoFinder	1	1.000	-	-		FOG0000490
OrthoInspector	1	1.000	-	-		mtm1038
orthoMCL	1	0.900	-	-		OOG6_100898
Panther	1	1.100	-	-	O	PTHR10623
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X303
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840