Protein Alignment Eb1 and Mapre2

DIOPT Version :10

• Sequence 1: NP_724495.2
• Gene: Eb1 / 35584
• FlyBaseID: FBgn0027066
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001094470.1
• Gene: Mapre2 / 679221
• RGDID: 1590736
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 320
• Identity: 138/320 - (43%)
• Similarity: 196/320 - (61%)
• Gaps: 59/320 - (18%)

  Fly     1 MAVNVYSTNVTSENLSRHDMLAWVNDCLQSQFSKIEELCTGAAYCQFMDMLFPNSVPVKRVKFRT 65
            ||||||||::|.|.:||||::|||||.:...::|:|:||:|||||||||||||..:.:|:|||:.
  Rat    43 MAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQA 107

  Fly    66 NLEHEYIQNFKILQAGFKKMSVDKIIPVDKLIKGRFQDNFEFLQWFKKFFDANYDGREYDPVAQR 130
            .||||||.|||:|||.||:|:|||:|||:||:|||||||.:|:||||||:||||||:|||||..|
  Rat   108 KLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEAR 172

  Fly   131 GG-------------VKLGNGNGHGSNGGSGVGSSNNDLHLMHRRPLQAPASGGRMPARVIASTA 182
            .|             ..|...:.|.::..:|...|:         |...|   |..|:|
  Rat   173 QGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSS---------PAAKP---GSTPSR------ 219

  Fly   183 VSKVLPRTNNAAPASRINACANSTGTVKKNDVSNSVNNQQIEEMSNQVMDMRINLEGLEKERDFY 247
                        |:|...  |:|:|:..::|.....   |:.:::.||..:::.|||:|||||||
  Rat   220 ------------PSSAKR--ASSSGSASRSDKDLET---QVIQLNEQVHSLKLALEGVEKERDFY 267

  Fly   248 FSKLRDIEILCQEADDAEAHPIIQKILDILYATEDGFAPP----------DDAPPEDEEY 297
            |.|||:||:|||| ...|...::|:::::|||:::.....          |..|.:.|||
  Rat   268 FGKLREIELLCQE-HGQENDDLVQRLMEVLYASDEQEGQTEEPEVEEQTHDQQPQQQEEY 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eb1	NP_724495.2	BIM1	16..293	CDD:227542	125/299 (42%)
Mapre2	NP_001094470.1	BIM1	58..315	CDD:227542	123/292 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..239		17/100 (17%)
		DCTN1-binding. /evidence=ECO:0000250	186..326		46/175 (26%)
		APC-binding. /evidence=ECO:0000250	258..301		24/43 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..326		5/28 (18%)