Protein Alignment phtf and Phtf2

DIOPT Version :10

• Sequence 1: NP_610232.1
• Gene: phtf / 35583
• FlyBaseID: FBgn0028579
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: XP_036021353.1
• Gene: Phtf2 / 68770
• MGIID: 1916020
• Length: 751
• Species: Mus musculus
• Alignment Length: 943
• Identity: 314/943 - (33%)
• Similarity: 438/943 - (46%)
• Gaps: 262/943 - (27%)

  Fly     2 KLDEIVAWYQKRIGTYDKQEWEKTVEQRILDGFNSVNLKNTKLKT-----ELIDVDLVRGSTFPK 61
            ::.:.:.||||:||.||:|.|||:||||.:. |..:.|:|...||     :||||||||||.|.|
Mouse     4 RVTDAIVWYQKKIGAYDQQIWEKSVEQREIK-FIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAK 67

  Fly    62 AKPKQSLLTVIRLAILRYVLLPLYAQWWVKQTTPNAFGFILVLYLTQLTNWAIYVLHSSRIVPLD 126
            |||:....::.|..|:|.|..|.:::||::.|:...|.::|||||.|:   |..||..|...|
Mouse    68 AKPESPWTSLTRKGIVRVVFFPFFSRWWLQVTSRVIFSWLLVLYLLQV---AAIVLFCSAPSP-- 127

  Fly   127 YEKPPNGTLLQAEADGDASDKDADKESEEHAALLSALLIPCALSLLISLIHSQIVATNTASGV-- 189
                                         |:..|:.::.|..|.||:..:|.|||:|.|....
Mouse   128 -----------------------------HSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLG 163

  Fly   190 SGGSSKNKLRRISASYLSDKAATRENRVRRRKKIVRVRQVEADLSQASSNISLPNRRTATSTIEV 254
            :||..:.|||         |||..|  |.|          |.|.|..:.|
Mouse   164 TGGKRRRKLR---------KAAHLE--VHR----------EGDGSSTTDN--------------- 192

  Fly   255 LPRPVTPLPSPTVTCATVPDPTTPTTPSPSVIRRSTNEETYLTTTAISPLTQPLAAIDACYDLSR 319
                                                              ||..|.        :
Mouse   193 --------------------------------------------------TQEGAV--------Q 199

  Fly   320 KAGGAAPESPKKRNVNWHTPIQIYATYELGEEPCSSRKVAEESAPESVGERLCSVKPDYQTRRNI 384
            ..|..||.|..          .::....|.....|..|.|:.|..:|.           :|
Mouse   200 SHGAGAPYSVG----------TVFRDLWLAAFFLSGSKKAKNSIDKST-----------ET---- 239

  Fly   385 GEDDGFESLNGKSS--SGED--NNHSPLPNAV-------AVAAP-PAPVQTNQLRLRLNTTNGVT 437
              |:|:.||:||.:  |.||  ..|.|....|       |...| ..|.:..|.:: .|.::.|:
Mouse   240 --DNGYVSLDGKRTVKSSEDGAQYHEPQCETVGPEDAAWATRTPRSVPAKDTQRKI-TNVSDEVS 301

  Fly   438 ASASPTEKKPQSRGNESSTS---------------CAESDECDDADIMSSPASG--CNQECTTSA 485
            :...|....| .||:...||               .|..|         :|.||  |:..|::|.
Mouse   302 SEEGPETGYP-LRGHVDRTSESGLRNRKPHHYKKHYANED---------APKSGTSCSSRCSSSR 356

  Fly   486 TDWLGVTTNSEDCSYTSDLDHSDGGLKHTA------FSDEDPGELDITP---------------- 528
            .|.......||    |.|:...|  |.|.|      .|:.|.|...|.|
Mouse   357 QDSESTRPESE----TEDVLWED--LLHCAECRSSCTSETDVGNPQINPCGKKEYRDDPFHQSHL 415

  Fly   529 TTILNPHSSLDRISCTIWDQRDAKKAQLSVLEIASCIIERVDSMGEANDYIYIGVVFSFLLTLIP 593
            ..:.:.|..|::||..:|:..|.|||.:|||||:..|:.||::......|...|...|.:|.|.|
Mouse   416 PWLHSSHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNNHVPGIGYQVFGNAISLILGLTP 480

  Fly   594 IFCRLCEVTLGSDAEKASEISYFNMPQLLWEKSSASLFTLLGLAFGDSQWERMVLA---LGFVQR 655
            ...||.:.|   |.|:            |...|::.|:.   :|||.:: :.|||:   :.||.|
Mouse   481 FVFRLSQAT---DLEQ------------LTAHSASELYV---IAFGSNE-DVMVLSMVLISFVVR 526

  Fly   656 LCLTLILFIIFAVAERTFKQRFLYAKLFSHLTSSRRARKSNLPHFRLNKVRNIKTWLSVRSYLKK 720
            :.|..|.|.:..|||||:|||.|:||||.||||:||||||.:|||||.||:|||.|||:|||||:
Mouse   527 VSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKR 591

  Fly   721 RGPQRSVDIIVSAAFIVTLLLLAFLSVEWLKDSAHLH-----THLTLEALIWSITIGIFLLRFMT 780
            ||||||||:|||:||::|:.::.....:.|    |:|     .|...|.:||.|::.:|||||:|
Mouse   592 RGPQRSVDVIVSSAFLLTISVVFICCAQLL----HVHEIFLDCHYNWELVIWCISLTLFLLRFVT 652

  Fly   781 LGQKIQHKYRSVSVLITEQINLYLQIEQKPKKKDELMVSNSVLKLAADLLKELETPFKLSGLSAN 845
            ||.:...||.:.|:|:||||||||::|:||.||:||.:.|:|||||..|||||::||:|.||:.|
Mouse   653 LGSETSKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMN 717

  Fly   846 PYLFTTIKVVILSALSGVLSEVLGFKLKLHKIK 878
            |.|:...:||||||:|||:|::|||.|||.|||
Mouse   718 PLLYNITQVVILSAVSGVISDLLGFNLKLWKIK 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtf	NP_610232.1	PHTF1-2_N	1..185	CDD:463466	67/187 (36%)
Phtf2	XP_036021353.1	PHTF1-2_N	3..158	CDD:463466	67/188 (36%)