Protein Alignment phtf and Phtf2

DIOPT Version :10

• Sequence 1: NP_610232.1
• Gene: phtf / 35583
• FlyBaseID: FBgn0028579
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: NP_001100047.2
• Gene: Phtf2 / 296762
• RGDID: 1310593
• Length: 747
• Species: Rattus norvegicus
• Alignment Length: 938
• Identity: 311/938 - (33%)
• Similarity: 436/938 - (46%)
• Gaps: 256/938 - (27%)

  Fly     2 KLDEIVAWYQKRIGTYDKQEWEKTVEQRILDGFNSVNLKNTKLKTELIDVDLVRGSTFPKAKPKQ 66
            ::.:.:.||||:||.||:|.|||:||||.:.|..:...|...:|.:||||||||||.|.||||:.
  Rat     4 RVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPES 68

  Fly    67 SLLTVIRLAILRYVLLPLYAQWWVKQTTPNAFGFILVLYLTQLTNWAIYVLHSSRIVPLDYEKPP 131
            ....:.|..|:|.|..|.:.:||::.|:...|.::|||||.|:   |..||..|...|
  Rat    69 PWTALTRKGIVRVVFFPFFFRWWLQVTSKVIFSWLLVLYLLQV---AAIVLFCSAPSP------- 123

  Fly   132 NGTLLQAEADGDASDKDADKESEEHAALLSALLIPCALSLLISLIHSQIVATNTASG--VSGGSS 194
                                    |:..|:.::.|..|.||:..:|.|||:|.|...  .:||..
  Rat   124 ------------------------HSIPLTEVIGPVWLMLLLGTVHCQIVSTRTPKPPLSTGGKR 164

  Fly   195 KNKLRRISASYLSDKAATRENRVRRRKKIVRVRQVEADLSQASSNISLPNRRTATSTIEVLPRPV 259
            :.|||         |||..|  |.|          |.|.|..:.|       |...|::
  Rat   165 RRKLR---------KAAHLE--VHR----------EGDGSSTTDN-------TQEGTVQ------ 195

  Fly   260 TPLPSPTVTCATVPDPTTPTTPSPSVIRRSTNEETYLTTTAISPLTQPLAAIDACYDLSRKAGGA 324
                                                      ||                  |..
  Rat   196 ------------------------------------------SP------------------GAG 200

  Fly   325 APESPKK--RNVNWHTPIQIYATYELGEEPCSSRKVAEESAPESVGERLCSVKPDYQTRRNIGED 387
            ||.|...  |:: ||....:           |..|..:.|..:|.           :|      |
  Rat   201 APYSVGSVFRDL-WHAAFLL-----------SGSKKTKNSIDKST-----------ET------D 236

  Fly   388 DGFESLNGKSS--SGED--NNHSPL-------PNAVAVAAPPAPVQTNQLRLRLNTTNGVTASAS 441
            :|:.||:||.:  |.||  .:|.|.       ..|.|...|.:....:..|...|.::.|::...
  Rat   237 NGYVSLDGKRTVKSSEDGAQDHEPQCETIRPEDTAWATRTPRSVPAKDAQRKITNVSDEVSSEEG 301

  Fly   442 PTEKKP-QSRGNESSTS-------------CAESDECDDADIMSSPASG--CNQECTTSATDWLG 490
            |....| :..|:.:|.|             .|..|         :|.||  |:..|::|..|...
  Rat   302 PETGYPSRCHGDRTSESGLRNRKPHHYKKHYANED---------APKSGTSCSSRCSSSRQDSES 357

  Fly   491 VTTNSEDCSYTSDLDHSDGGLKHTA------FSDEDPGELDITP----------------TTILN 533
            ....||    |.|:...|  |.|.|      .|:.|.|...|.|                ..:.:
  Rat   358 TRPESE----TEDVLWED--LLHCAECRSSCTSETDVGNPQINPCGKKEYRDDPFHQTHLPWLHS 416

  Fly   534 PHSSLDRISCTIWDQRDAKKAQLSVLEIASCIIERVDSMGEANDYIYIGVVFSFLLTLIPIFCRL 598
            .|..|::||..:|:..|.|||.:|||||:..|:.||::......|...|...|.:|...|...||
  Rat   417 SHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNNHVPGIGYQIFGNAVSLILGFTPFVFRL 481

  Fly   599 CEVTLGSDAEKASEISYFNMPQLLWEKSSASLFTLLGLAFGDSQWERMVLA---LGFVQRLCLTL 660
            .:.|   |.|:            |...|::.|:.   :|||.:: :.|||:   :.||.|:.|..
  Rat   482 SQAT---DLEQ------------LTAHSASELYV---IAFGSNE-DFMVLSMVLISFVVRVSLVW 527

  Fly   661 ILFIIFAVAERTFKQRFLYAKLFSHLTSSRRARKSNLPHFRLNKVRNIKTWLSVRSYLKKRGPQR 725
            |.|.:..|||||:|||.|:||||.||||:||||||.:|||||.||:|||.|||:|||||:|||||
  Rat   528 IFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQR 592

  Fly   726 SVDIIVSAAFIVTLLLLAFLSVEWLKDSAHLH-----THLTLEALIWSITIGIFLLRFMTLGQKI 785
            |||:|||:||::|:.::.....:.|    |:|     .|...|..||.|::.:|||||:|||.:.
  Rat   593 SVDVIVSSAFLLTISVVFVCCAQLL----HVHEIFLDCHYNWELAIWCISLSLFLLRFVTLGSET 653

  Fly   786 QHKYRSVSVLITEQINLYLQIEQKPKKKDELMVSNSVLKLAADLLKELETPFKLSGLSANPYLFT 850
            ..||.:.|:|:||||||||::|:||.||:||.:.|:|||||..|||||::||:|.||:.||.|:.
  Rat   654 SKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYN 718

  Fly   851 TIKVVILSALSGVLSEVLGFKLKLHKIK 878
            ..:||||||:|||:|::|||.|||.|||
  Rat   719 ITQVVILSAVSGVISDLLGFNLKLWKIK 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtf	NP_610232.1	PHTF1-2_N	1..185	CDD:463466	65/182 (36%)
Phtf2	NP_001100047.2	PHTF1-2_N	3..154	CDD:463466	65/183 (36%)