Protein Alignment phtf and phtf

DIOPT Version :10

• Sequence 1: NP_610232.1
• Gene: phtf / 35583
• FlyBaseID: FBgn0028579
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: XP_316489.5
• Gene: phtf / 1277061
• VectorBaseID: AGAMI1_005626
• Length: 1072
• Species: Anopheles gambiae
• Alignment Length: 1128
• Identity: 472/1128 - (41%)
• Similarity: 605/1128 - (53%)
• Gaps: 304/1128 - (26%)

  Fly     1 MKLDEIVAWYQKRIGTYDKQEWEKTVEQRILDGFNSVNLKNTKLKTELIDVDLVRGSTFPKAKPK 65
            |:||.:||||||:|||||||:||||:||:||.|.:.:.|||||||||||||||||||||||||.|
Mosquito     1 MRLDALVAWYQKKIGTYDKQQWEKTIEQKILAGISHLPLKNTKLKTELIDVDLVRGSTFPKAKSK 65

  Fly    66 QSLLTVIRLAILRYVLLPLYAQWWVKQTTPNAFGFILVLYLTQLTNWAIYVLHSSRIVPLDYEKP 130
            .|:|||:.||.||::|||:||:|||:||:|..|..:|.|||.|:.|..||...:....|:    |
Mosquito    66 LSILTVLYLAALRFLLLPVYARWWVQQTSPGVFLLLLTLYLLQMLNLGIYSYCARSPSPV----P 126

  Fly   131 PNGTLLQAEADG-DASDKDADKESEEHAALLSALLIPCALSLLISLIHSQIVATNTASGVSGGSS 194
            |:.|.....:|| :.:.|....::.:|...:|..|||.|||||:|:|||||||  |||. |.|||
Mosquito   127 PSSTDTATGSDGAEPNAKLPPTDTVDHIVTISDFLIPLALSLLLSVIHSQIVA--TASN-SNGSS 188

  Fly   195 KNKLRRISASYLSDKAAT------------------------------RENRVRRRKKIVRVRQV 229
            .....::|....|..:||                              ||.|:||::::....:.
Mosquito   189 LFSCGKLSQKCFSHGSATPATPGAASTGTGTSLSTPAGGVPAGLSKKQREQRIRRKRRVRAHSET 253

  Fly   230 EADLSQASSNISLPNR------------RTATSTIEVLPRPVTPLPSPTVTCATVPDPTTPTTPS 282
            :|..|.....::...|            ::|||:      |....|... .|:     |:.:|.|
Mosquito   254 QAQSSSPGRAVTAEERDRKKAFASVGGSKSATSS------PARTAPKKG-ACS-----TSSSTSS 306

  Fly   283 PSV--------------------------------------IRRSTNEETYLTTTAISPLTQPLA 309
            .:|                                      |.|:.||....|:..::.:....:
Mosquito   307 DAVERAQLAEGNSNEQQRQPEVLVGRREENGSLRMEDRAPNIHRTANETEKHTSIGVTIIPSTNS 371

  Fly   310 AIDACYDLSRKAGG---------AAPESPKKRNVNWHTPIQIYATYELGEEPCSSRKVAEESAPE 365
            :.|......|::|.         ..|...::|||||...:           |..||     ..|.
Mosquito   372 SSDHSPPNGRRSGDHTQEANPMLLLPSGLRRRNVNWDPTV-----------PERSR-----PGPS 420

  Fly   366 SVGERLCSVKPDYQTRRNIGEDDGFESLNGKSSSGED--------NNH-----SPLPNAVAVAAP 417
            |:      ::|       :.:||||||||||||.|||        ::|     :|.......||.
Mosquito   421 SL------LEP-------VVDDDGFESLNGKSSGGEDSAGNVFLKDHHRYRKVAPFGGNDWNAAG 472

  Fly   418 PAPVQTNQLRLRLNT-TNGVTASAS----PT---------------------------------- 443
            ....:.:|.....:| .|.:|.:.|    ||
Mosquito   473 ETEAKDHQSDSDTDTLKNSITTTTSNYNTPTIAELDGVLDPQRKQFTEGGYTAGSQLELAQHDTP 537

  Fly   444 ------EKKP---QSRGNESS------------------------TSCAESDECDDAD------- 468
                  |.|.   |.|..:||                        |||  |||.|:.:
Mosquito   538 QHGGRGESKELVRQRRNKDSSKQPLQRRAPTALYDVGPDEKKGLGTSC--SDETDEENNEYDLHS 600

  Fly   469 ----------------------------IMSSPASGCNQE------------------------- 480
                                        :..|||......
Mosquito   601 PSPPHLHLLHSSPPLRAHHPHQPMVGPVVRPSPAGSSPSPHHHHHHLLYLHHRHHQAAAVVQPAA 665

  Fly   481 -CTTSATDW-----------LGVTTNSEDCSYTSDLDHSDGGLKHTAFSDEDPGELDITPTTILN 533
             .|.:|...           ..|.|..|:|||:|:|||||...:|   ||:| .||:..||.|||
Mosquito   666 VATAAAHSHHTLHPHHFHHSPSVLTEGEECSYSSELDHSDTQNEH---SDDD-YELEDVPTLILN 726

  Fly   534 PH-SSLDRISCTIWDQRDAKKAQLSVLEIASCIIERVDSMGEANDYIYIGVVFSFLLTLIPIFCR 597
            |. .:.||:|||||:.|:||||::|||:|:|.|||||::|.|:.||:|||||.|..|:|:|.|||
Mosquito   727 PACGANDRVSCTIWEAREAKKAEMSVLDISSAIIERVEAMPESCDYVYIGVVLSVFLSLVPAFCR 791

  Fly   598 LCEVTLGSDAEKASEISYFNMPQLLWEKSSASLFTLLGLAFGDSQWERMVLALGFVQRLCLTLIL 662
            |||.|:  |:..::|:::.:||.:|:||:|.||..:|..|||::.|||.||.|||:.||.||.::
Mosquito   792 LCEATV--DSTNSTEVNFLDMPVILFEKASFSLLAILRFAFGETTWERFVLVLGFLLRLVLTFLV 854

  Fly   663 FIIFAVAERTFKQRFLYAKLFSHLTSSRRARKSNLPHFRLNKVRNIKTWLSVRSYLKKRGPQRSV 727
            |.:.||||||||||||||||||||||||||:||.:|||||||||||||||.||||||:||||.||
Mosquito   855 FFLLAVAERTFKQRFLYAKLFSHLTSSRRAQKSGIPHFRLNKVRNIKTWLCVRSYLKRRGPQNSV 919

  Fly   728 DIIVSAAFIVTLLLLAFLSVEWLKDSAHLHTHLTLEALIWSITIGIFLLRFMTLGQKIQHKYRSV 792
            |:|||||||:||||||||||||||||.|||:...||||.||...|.|||||||||.||..||:||
Mosquito   920 DVIVSAAFIITLLLLAFLSVEWLKDSVHLHSQFNLEALTWSCAFGTFLLRFMTLGTKINKKYKSV 984

  Fly   793 SVLITEQINLYLQIEQKPKKKDELMVSNSVLKLAADLLKELETPFKLSGLSANPYLFTTIKVVIL 857
            |||||||||||:||||||.||:|||:||:|||||||||||||:|||:|||||||||:||:|||||
Mosquito   985 SVLITEQINLYVQIEQKPNKKEELMISNNVLKLAADLLKELESPFKISGLSANPYLYTTVKVVIL 1049

  Fly   858 SALSGVLSEVLGFKLKLHKIKIK 880
            |||||||||:|||||||||||||
Mosquito  1050 SALSGVLSEMLGFKLKLHKIKIK 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtf	NP_610232.1	PHTF1-2_N	1..185	CDD:463466	104/184 (57%)
phtf	XP_316489.5	None