Protein Alignment phtf and phtf1

DIOPT Version :10

• Sequence 1: NP_610232.1
• Gene: phtf / 35583
• FlyBaseID: FBgn0028579
• Length: 880
• Species: Drosophila melanogaster
• Sequence 2: XP_012811003.1
• Gene: phtf1 / 100144741
• XenbaseID: XB-GENE-853450
• Length: 742
• Species: Xenopus tropicalis
• Alignment Length: 909
• Identity: 281/909 - (30%)
• Similarity: 439/909 - (48%)
• Gaps: 209/909 - (22%)

  Fly     5 EIVAWYQKRIGTYDKQEWEKTVEQRILDGFNSVNLKNTKLKTELIDVDLVRGSTFPKAKPKQSLL 69
            :.::|||::||.||||.|||:|||..:.|..:...|...:|::||||||||||||.|.||:....
 Frog     7 DAISWYQEKIGAYDKQIWEKSVEQTEIKGLRTKPKKMVSIKSDLIDVDLVRGSTFAKTKPESPWT 71

  Fly    70 TVIRLAILRYVLLPLYAQWWVKQTTPNAFGFILVLYLTQLTNWAIYVLHSSRIVPLDYEKPPNGT 134
            ::.|..::|.||.||:.:|||:.|:|..|.::|::|:.|:.....|     .:||:
 Frog    72 SLTRKGLVRVVLFPLFCKWWVQVTSPGVFIWLLIIYILQVMAIVFY-----SMVPV--------- 122

  Fly   135 LLQAEADGDASDKDADKESEEHAALLSALLIPCALSLLISLIHSQIVATNTA--SGVSGGSSKNK 197
                                   |.:|..:.|..|.||:..:|.|||:|.::  ||:.|.
 Frog   123 -----------------------ASISEQIGPLCLMLLLGTVHCQIVSTRSSRTSGIGGN----- 159

  Fly   198 LRRISASYLSDKAATRENRVRRRKKIVRVRQVEADLSQASSNISLPNRRTATSTIEVLPRPVTPL 262
             :|:...|....:...:|.:::|.|..         |..:...|....|..|..:.
 Frog   160 -KRLRTKYRKSMSPDEDNTLKKRFKTT---------SSGNRFRSFLYNRVKTENLS--------- 205

  Fly   263 PSPTVTCATVPDPTTPTTPSPSVIRRSTNEETYL----TTTAISPLTQPLAAIDACYDLSRKAGG 323
                                    ::..|:..||    |.......::|  .|..|    :....
 Frog   206 ------------------------KKVHNKGGYLHNVHTVARDKNSSRP--GIHHC----KNEAS 240

  Fly   324 AAPESPKKRNVN--WH---TPIQIYATYELGEEPCSSRKVAEESAPESVGERLCSVKPDYQTRRN 383
            .|.:|..:.|.|  |.   :...|.|..|:..   .||.:.|.|:     :..|::     |:||
 Frog   241 DAEKSELRMNGNGVWEDLTSEEDIDAKNEMSS---LSRSIEEASS-----DIACTL-----TKRN 292

  Fly   384 ---IGEDDGFESLNGKSSSGEDNNHSPLPNAVAVAAPPAPVQTNQLR-LRLNTTNGVTASASPTE 444
               :......|.|..:|....:::              :||:|.:.. |...:.:|:  |.|...
 Frog   293 LHSVANRSTQEKLKKESQPSWESD--------------SPVETEEESFLSQGSRSGI--SCSSHS 341

  Fly   445 KKPQSRGNESSTSCAESDECDDADIMSSPASGCNQECTTSATDWLGVTTNSEDCSYTSDLD---- 505
            .....|.:||:...:|:::....|::..|      :|.:               ||.||.|
 Frog   342 YSISHRDSESTRQGSETEDMIMDDLLHGP------QCLS---------------SYESDSDDIFS 385

  Fly   506 --HSDGGLKHTAFSDEDPGEL-------DITPTTILNPHSSLDRISCTIWDQRDAKKAQLSVLEI 561
              :::|..|   .|.:|..:|       |.:||:        .::|..||::.:.||..:|||:|
 Frog   386 HSYNEGNRK---ASTKDVFQLNHLFWLQDTSPTS--------KKVSALIWEREECKKIDMSVLDI 439

  Fly   562 ASCIIERVDSMGEANDYIYIGVVFSFLLTLIPIFCRLCEVTLGSDAEKASEISYFNMPQLLWEKS 626
            :..|:::|:|......|..:|.:.:..|.:.|....||.   ..|.|....:|...:.::....:
 Frog   440 SGVIMKQVNSYKHGLGYQMLGNLVTLCLAIFPFLFNLCH---SRDVEHIISVSREELLEVFCGGT 501

  Fly   627 SASLFTLLGLAFGDSQWERMVLALGFVQRLCLTLILFIIFAVAERTFKQRFLYAKLFSHLTSSRR 691
            ...|  :|.|:|           :.||.|.|||.|.|....|||||:|||||.|||||||||:|:
 Frog   502 PTPL--VLTLSF-----------INFVLRACLTWIFFFFMCVAERTYKQRFLIAKLFSHLTSARK 553

  Fly   692 ARKSNLPHFRLNKVRNIKTWLSVRSYLKKRGPQRSVDIIVSAAFIVTLLLLAFLSVEWLKDSAHL 756
            |.|..:||||||||:|||.|||:|||||:||||||||:|||:.::||      ||:.::..:..|
 Frog   554 ALKYEIPHFRLNKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSVYLVT------LSIAFICCAQVL 612

  Fly   757 HTHLTL-------EALIWSITIGIFLLRFMTLGQKIQHKYRSVSVLITEQINLYLQIEQKPKKKD 814
            |.:.|.       |.|||...:.|||||..:||.:...||.:||||:||:||:||::|:||.||:
 Frog   613 HGYTTFLNSVYNWEFLIWETALLIFLLRLTSLGSETNKKYSNVSVLLTEEINVYLKMEKKPNKKE 677

  Fly   815 ELMVSNSVLKLAADLLKELETPFKLSGLSANPYLFTTIKVVILSALSGVLSEVLGFKLKLHKIK 878
            :|.:.|:||||::.|:||::|||:|.||..||.::...:||||||:|||:|::|||.::|.|||
 Frog   678 KLSLVNNVLKLSSKLIKEIDTPFRLYGLDVNPLIYNITRVVILSAVSGVVSDLLGFNIRLWKIK 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phtf	NP_610232.1	PHTF1-2_N	1..185	CDD:463466	62/179 (35%)
phtf1	XP_012811003.1	PHTF1-2_N	6..151	CDD:463466	62/180 (34%)