Protein Alignment Zip42C.2 and SLC39A3

DIOPT Version :9

• Sequence 1: NP_610231.2
• Gene: Zip42C.2 / 35580
• FlyBaseID: FBgn0033097
• Length: 310
• Species: Drosophila melanogaster
• Sequence 2: NP_653165.2
• Gene: SLC39A3 / 29985
• HGNCID: 17128
• Length: 314
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 91/323 - (28%)
• Similarity: 154/323 - (47%)
• Gaps: 51/323 - (15%)

  Fly     6 LIVAKIVAIVVLFLVTLIFCFIPYLLDRFYKWTQRPENNAREFKVVLCLLN-FGGGVLIATTFIH 69
            |:||||:.:|.:|...|:...:|      .|..:.....|...|.:|.|.| |||||.:||.|..
Human     4 LLVAKILCMVGVFFFMLLGSLLP------VKIIETDFEKAHRSKKILSLCNTFGGGVFLATCFNA 62

  Fly    70 MLPEVVEVVNALQDCRMLAPTPFGLPEVLLCTGFYLMYCIEETMHFVVRRRQQRKLREVVTI--- 131
            :||.|.|.:..:.....:: |.:.|.|.:|..||::...:|:.:  :..|:::....::.|.
Human    63 LLPAVREKLQKVLSLGHIS-TDYPLAETILLLGFFMTVFLEQLI--LTFRKEKPSFIDLETFNAG 124

  Fly   132 KDAGEELRTE-----------IVVQP-------------EESPKEPNWLRGLGIIVALSLHELFG 172
            .|.|.:...|           :.|:|             ..||     :|.|.:..|||.|.:|.
Human   125 SDVGSDSEYESPFMGGARGHALYVEPHGHGPSLSVQGLSRASP-----VRLLSLAFALSAHSVFE 184

  Fly   173 GMAIGLEMSVSTVWFMTGAISVHKLVLAFCIGMEIMMAHTRWLL--AVVYLLVFSIVTPIGVGIG 235
            |:|:||:.....|..:...::||:.::|..:|  |.||.:...|  |....:..|.:.|:|:|:|
Human   185 GLALGLQEEGEKVVSLFVGVAVHETLVAVALG--ISMARSAMPLRDAAKLAVTVSAMIPLGIGLG 247

  Fly   236 IAVSESAAANQPSTVSGILQGLACGTLIYVVFFEIVAK--NHAGIRIL--LSSMVGFVLMFGL 294
            :.: |||.....|..|.:|||||.||.:::.|.||:||  .....|:|  |..::|:.::.|:
Human   248 LGI-ESAQGVPGSVASVLLQGLAGGTFLFITFLEILAKELEEKSDRLLKVLFLVLGYTVLAGM 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip42C.2	NP_610231.2	Zip	9..294	CDD:280666	88/318 (28%)
SLC39A3	NP_653165.2	Zip	5..309	CDD:396884	89/320 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1558
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H44230
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4770
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D471714at33208
OrthoFinder	1	1.000	-	-		FOG0000574
OrthoInspector	1	1.000	-	-		mtm8626
orthoMCL	1	0.900	-	-		OOG6_100840
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X561
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.730