DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip42C.1 and Slc39a3

DIOPT Version :9

Sequence 1:	NP_525107.1	Gene:	Zip42C.1 / 35579	FlyBaseID:	FBgn0033096	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001008357.1	Gene:	Slc39a3 / 314637	RGDID:	1310863	Length:	317	Species:	Rattus norvegicus

Alignment Length:	349	Identity:	105/349 - (30%)
Similarity:	160/349 - (45%)	Gaps:	66/349 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLVAKIVSMVVLVVITVLCGSLPY-VLNRCFHWTKASPEETRSSLVVRCLLFFGGGVLICTTFLH 83
            |||||::.||.:....:|...||. |:...|.  ||.    ||..|:.....|||||.:.|.|..
  Rat     4 LLVAKVLCMVGVFFFMLLGSLLPVKVIEADFE--KAH----RSKKVLSLCNTFGGGVFLATCFNA 62

  Fly    84 MLPEVIEVVEALQECGSLVKTPFALAEMLLCTGFFLMYALDELMTSLVRH----------HQGKL 138
            :||.|.:.::.:...|. :.|.:.|||.|:..||||...:::|:.:..|.          :.|..
  Rat    63 LLPAVRDKLQQVLSLGH-ISTDYPLAETLMMVGFFLTVFVEQLVLTFRRERPPFIDLETFNAGSD 126

  Fly   139 SRKESVASLAFERGRSIRHSVLLNPQAKEEVEVKDTEPQPHKDHHGHSH----------MPVPAD 193
            :..:|.....|.......|.:...|.|                   |||          .|.|
  Rat   127 AGSDSEYESPFVGVGGRNHGLYPEPTA-------------------HSHGTGLRLRELGRPGP-- 170

  Fly   194 DGSSARGLGIILALSLHELFEGMAIGLEGTVSTVWFMFGAVSAHKLVLAFCVGMELLVARTRSSL 258
                .|.|.::.|||.|.:|||:|:||:.....|..:|..|:.|:.::|..:|:.:  ||:...|
  Rat   171 ----LRLLSLVFALSAHSVFEGLALGLQEEGERVVSLFVGVAVHETLVAVALGISM--ARSAVPL 229

  Fly   259 --AILYLVTFSIVTPIGIGVGLGI--SQQVAAGQPSLPSGVLQGIACGTLLYVVFFEILI----E 315
              |....||.|.:.|:|||:||||  ::.||:   |:.|.:|||:|.||.|:|.|.|||.    |
  Rat   230 RDAAKLAVTVSAMIPVGIGLGLGIESARSVAS---SVASALLQGLAGGTFLFVTFLEILAKELEE 291

  Fly   316 SHAGWRALVAAVAGFALMFGLQIL 339
            .......::..|.|:|::.|:..|
  Rat   292 RSEQLLKVLFLVLGYAVLAGMVFL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip42C.1	NP_525107.1	Zip	21..336	CDD:280666	102/343 (30%)
Slc39a3	NP_001008357.1	Zip	5..312	CDD:396884	102/343 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353023
Domainoid	1	1.000	116	1.000	Domainoid score	I5803
eggNOG	1	0.900	-	-		E1_KOG1558
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H44230
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4700
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D471714at33208
OrthoFinder	1	1.000	-	-		FOG0000574
OrthoInspector	1	1.000	-	-		mtm9105
orthoMCL	1	0.900	-	-		OOG6_100840
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X561
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.700