Protein Alignment chk and slc16a13

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_001920250.3
• Gene: slc16a13 / 793210
• ZFINID: ZDB-GENE-120907-2
• Length: 502
• Species: Danio rerio
• Alignment Length: 770
• Identity: 145/770 - (18%)
• Similarity: 239/770 - (31%)
• Gaps: 360/770 - (46%)

  Fly   133 PDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIWSN 197
            ||||:|||||.|..|:|.:..||..|.|:..||.::||.||....:||:|:..::..||.||.:.
Zfish    20 PDGGWGWVVVGALFVISALVFGLIRSLGVFFVEFVQYFDESAQAVSWITSIGLAMQQLMSPIGAA 84

  Fly   198 LVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDKKR 262
            ..:.||.|.:.::||.:|..||.|:|...|:..|.:|.|:|||||..:.:...:.|:..:|.|:|
Zfish    85 ASNVYGTRPVVMMGGFLSGLGFILASQATSLLHLYLTMGLISGLGWALVFTPTMASVMQYFTKRR 149

  Fly   263 TFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDWLIEENRLE 327
            :.|.|:|.:|.|:.:|.::.|..||:|:|.||||.|||||...|...||||:|
Zfish   150 SLAMGLGFTGVGLASFAFSPLFQYLVEAYAWRGALLILGGLSFNMVACGALIR------------ 202

  Fly   328 SRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSEIFL 392
                                   ..|..|.||    .|:|:|:.|
Zfish   203 -----------------------PLGTPKVAV----KTENSTKLN-------------------- 220

  Fly   393 PTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLMGGI 457
                                                                             
Zfish   221 ----------------------------------------------------------------- 220

  Fly   458 AHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAKHTT 522
                    |.::|.|
Zfish   221 --------KCSFLLS-------------------------------------------------- 227

  Fly   523 PSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVNSELATRRA 587
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   588 RLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSC 652
                                                                        |...|
Zfish   228 ------------------------------------------------------------RIYEC 232

  Fly   653 PNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFIIPYLYLPDY 717
                                          |:.||.....|..:.::..|....:.|||::|..:
Zfish   233 ------------------------------FELSLLTHRGFVTYAVAITFFNAGYFIPYVHLVAH 267

  Fly   718 MKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICYSLCMLV-----CGASVFFMPL 777
            .:...:...|:|.:||..|:|..||.:..|:..||..:.:     |.|||     .|.|:..:|:
Zfish   268 SRHIGFTEYQAAFVISITGVADIVGRVASGWASDLGKIRL-----LHMLVVWTGLLGLSLMLIPV 327

  Fly   778 LITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIY 842
            .:. |.||:::.:::||...:......:::..||.::....|.||:.|::..|.:.|.|::|.:.
Zfish   328 AVV-YAGLLLVSIVYGFCAGAMAPLAFAVVPEIVGIERVLGALGLLQLIESAGGLLGAPLSGWLK 391

  Fly   843 EYTGRWDDTFYYAGIFIALSGVCSYLIEF---C---------EKKAPKESDSDVL 885
            :.||.:..:|..||.|:.:..:.:..:.:   |         :||:.:.|..|.|
Zfish   392 DSTGTYTVSFIAAGSFLMIGMLIAMTLPYFWSCTAPPAPSPSKKKSQEGSAEDGL 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	68/171 (40%)
		MFS	<685..869	CDD:119392	47/188 (25%)
slc16a13	XP_001920250.3	2A0111	11..443	CDD:331689	143/765 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm25394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.910