Protein Alignment chk and Slc16a9

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_080083.2
• Gene: Slc16a9 / 66859
• MGIID: 1914109
• Length: 508
• Species: Mus musculus
• Alignment Length: 760
• Identity: 168/760 - (22%)
• Similarity: 255/760 - (33%)
• Gaps: 283/760 - (37%)

  Fly   131 KMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIW 195
            |.||||:|||:|..|.....::.|...:.|::.||.|:.|||...||||:.||...|.||..|:.
Mouse     5 KSPDGGWGWVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVC 69

  Fly   196 SNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDK 260
            |..|..:|.|.:||..|.:.|.|..|||...:|..|..::||:.|||.|:.|...|.....:||.
Mouse    70 SLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDS 134

  Fly   261 KRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDWLIEENR 325
            :|..|.|:.::|:.:|.|:||.|...|||.||..|..||:|...||...||:|||
Mouse   135 RRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMR---------- 189

  Fly   326 LESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSEI 390
                                                                ||.::
Mouse   190 ----------------------------------------------------PLQTS-------- 194

  Fly   391 FLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLMG 455
                                           :.|              :|..||....||...|
Mouse   195 -------------------------------DCP--------------FPEKTAPENVPDRYSM- 213

  Fly   456 GIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHA------SSRYSLNEN 514
                         |         :||.   :.|..::...|:||.::...      ....||.::
Mouse   214 -------------Y---------NEKE---KNPEETMNFQDKGYSSEDKCLPNGDWGRETSLPKS 253

  Fly   515 IFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVN 579
            :.:|.||
Mouse   254 LAIAAHT---------------------------------------------------------- 260

  Fly   580 SELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHR 644
                                  |:|..::..:     :..:||.|              .|...:
Mouse   261 ----------------------KEPETYKKKV-----VEQTNFCK--------------QLAKRK 284

  Fly   645 YRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFII 709
            ::|        |||.....|                     |||.:..|:...::.|...|....
Mouse   285 WQL--------YRNYCGETA---------------------SLFKNKVFSALFIAILLFDIGGFP 320

  Fly   710 PYLYLPDYMKQYKY-DVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICYSLCMLVCGASVF 773
            |.|.:.|..:.|.. :...:..|||..||...||.:.||.|.|..|:|....|...:::.|.::.
Mouse   321 PSLLMEDVARSYHVREEDLTMPLISIFGIMTAVGKLLLGILADFKWINTLYLYVATLIITGLALC 385

  Fly   774 FMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIA 838
            .:| ...:|:.|.::..|.|| ...::|..|.:....|.:|....|||:::...|:|...||||.
Mouse   386 AIP-FAKSYVTLAILSGILGF-LTGNWSIFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIV 448

  Fly   839 GVIYEYTGRWDDTFYYAGIFIALSGVCSYLI-----EFCEKKAPK 878
            |..|::|..:|..||::|..:.|.|....|.     :.|.||.||
Mouse   449 GWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWDMCNKKLPK 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	66/171 (39%)
		MFS	<685..869	CDD:119392	53/184 (29%)
Slc16a9	NP_080083.2	MFS_MCT9	12..479	CDD:340986	157/737 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6905
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm11108
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810