Protein Alignment chk and slc16a7

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001032485.1
• Gene: slc16a7 / 641419
• ZFINID: ZDB-GENE-051113-248
• Length: 465
• Species: Danio rerio
• Alignment Length: 775
• Identity: 142/775 - (18%)
• Similarity: 224/775 - (28%)
• Gaps: 362/775 - (46%)

  Fly   129 TPKMPDGGYGWVVVFASLVVSLIADGLSFSF----GLINVELLEYFGESTSKTAWISSLFFSVPL 189
            ||  ||||:||.|||.    |.|:.|.|::|    .:...|:.|||..|.|:.||:||:..:...
Zfish    12 TP--PDGGWGWAVVFG----SFISIGFSYAFPKSLTIYFKEIQEYFSISYSQIAWVSSIMLATMY 70

  Fly   190 LMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSI 254
            ..||:.|.||::||.|.:.|.||::.......:||..||..|.:..|:|.|.||......|:..|
Zfish    71 AGGPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFDLQPALTII 135

  Fly   255 AFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDW 319
            ..:|..||..|.||..:|:.:.....|.:..:|.:.:||||:..||||.:.|.||.|:|||
Zfish   136 GKYFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMR---- 196

  Fly   320 LIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALK 384
                                                                             
Zfish   197 ----------------------------------------------------------------- 196

  Fly   385 RYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSP 449
                .|.:|...:|:  |:|                                   .|.||   ..
Zfish   197 ----PIKIPVSKTTE--DNI-----------------------------------SPQTA---GQ 217

  Fly   450 DDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNEN 514
            ||:
Zfish   218 DDS-------------------------------------------------------------- 220

  Fly   515 IFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVN 579
                                                                             
Zfish   221 ----------------------------------------------------------------- 220

  Fly   580 SELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHR 644
                                   |||...|.|.:.|
Zfish   221 -----------------------KPSGCSSKLNQFI----------------------------- 233

  Fly   645 YRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFII 709
                                                   |.|||....|.::.:..:.:|..|..
Zfish   234 ---------------------------------------DISLFKHRGFLIYLVGNVLMFFGFFA 259

  Fly   710 PYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICY---------SLCM 765
            |.::|..|.|....|...:|.|:|...:.......|.|.:.:..|:...|.|         .||.
Zfish   260 PVVFLAPYAKHQGVDEYSAAFLLSIFALVDMFARPGTGLVANTKWIRPKIQYFFSFAVTYNGLCH 324

  Fly   766 LVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVG 830
            |:|       ||| ..|:||:|..|:||..|....:....:|:.:|....|:.|.||..:::...
Zfish   325 LMC-------PLL-PGYIGLVVYAVLFGLAFGMVCALLFEVLMDLVGAQRFSSAVGLATIIECGP 381

  Fly   831 MIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFCE----KKAPKESDSDVLE 886
            ::.||||:|::.:....:...::..|:.:...||..:::.:..    ||..|:.:::.|:
Zfish   382 VLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVFLFIMNYYNYRWLKKEEKQRNAEELQ 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	61/175 (35%)
		MFS	<685..869	CDD:119392	48/192 (25%)
slc16a7	NP_001032485.1	2A0113	1..440	CDD:273325	141/772 (18%)
		MFS	20..420	CDD:119392	131/742 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm25394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.910