Protein Alignment chk and slc16a5a

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_021336012.1
• Gene: slc16a5a / 565514
• ZFINID: ZDB-GENE-121108-4
• Length: 506
• Species: Danio rerio
• Alignment Length: 772
• Identity: 143/772 - (18%)
• Similarity: 239/772 - (30%)
• Gaps: 349/772 - (45%)

  Fly   112 ISNESGD--SIDSSSTEKKTP------------KMPDGGYGWVVVFASLVVSLIADGLSFSFGLI 162
            :..:||:  ..:|...||:.|            ..||||:||||:.|:::|  :|..|:|...:|
Zfish     9 MEEQSGELCEPESEELEKQGPGPPSNANAPDSYDAPDGGWGWVVLLATIIV--LALTLAFPSCII 71

  Fly   163 --NVELLEYFGESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFC 225
              .::|.:.|..:.|:|:|:.|:..:|....||:.|.|||::|||...:.|||:|.||.|:|||.
Zfish    72 IFYLDLQKEFEATNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFS 136

  Fly   226 NSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIES 290
            :||..|.:|.|:|:|||....:..||..:..:|.::|.||..:.::||.:|......|..:|...
Zfish   137 HSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIE 201

  Fly   291 YGWRGATLILGGTMLNACVCGALMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGIT 355
            .||||:.|:||..:||.|||||:||.
Zfish   202 LGWRGSFLVLGAVLLNCCVCGAVMRP--------------------------------------- 227

  Fly   356 KEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEG 420
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   421 EEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTG 485
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   486 RTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYS 550
                                                                             
Zfish   228 ----------------------------------------------------------------- 227

  Fly   551 KDETFALLEPSRRIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNI 615
                         |||                                   :||       |:..
Zfish   228 -------------IRP-----------------------------------RKP-------RKTN 237

  Fly   616 SIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMK 680
            .|.||....|.         :|.||..         |.::                    ..:::
Zfish   238 EINNSPKTSDK---------KGCMLGI---------CQSL--------------------ASSLR 264

  Fly   681 SIFDFSLFL-DMKFALFNLSTLFLFIWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMI 744
            ....|.||. :.:|.:|:|...::.:.|::|.:||..|......|.|::|.|:|.:|........
Zfish   265 QQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRP 329

  Fly   745 GLGYLGDLSWMNINICY--SLCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSIL 807
            .:|.|..|.|......|  |..:|:.|.|.... .:..::..|:|..:.:|.:.:...|...::|
Zfish   330 PVGVLFSLPWFKGRHIYVFSAALLINGLSNSIC-CISASFPVLLVYVLTYGLSMSVVGSLMFTVL 393

  Fly   808 VSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGV 864
            :..|::..|..|.||:.:::.|.::.|||:||.:.:.|..:...|....|.:.||.:
Zfish   394 MDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYVFMACTIIVVLSAL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	66/173 (38%)
		MFS	<685..869	CDD:119392	47/183 (26%)
slc16a5a	XP_021336012.1	2A0111	38..457	CDD:331689	137/743 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm25394
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810