Protein Alignment chk and slc16a6a

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001243761.1
• Gene: slc16a6a / 564872
• ZFINID: ZDB-GENE-110208-1
• Length: 495
• Species: Danio rerio
• Alignment Length: 778
• Identity: 131/778 - (16%)
• Similarity: 248/778 - (31%)
• Gaps: 324/778 - (41%)

  Fly   131 KMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIW 195
            ::||||:||:|..|..:|.:...|:..|||:...:|:..|.|:.|:.:||.|:...|.....|:.
Zfish    19 EVPDGGWGWIVAVALFLVEVFTYGVIKSFGIFLKDLMSDFNETNSRVSWIISICVFVMTFTAPLS 83

  Fly   196 SNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDK 260
            :.|.:::|.:.:.:.||.:.:.|...::|.:||..:.:|.||.:|||..:.::.....::.:|.:
Zfish    84 TMLSNRFGFQPVVMFGGFLISLGTISTAFTSSINQMYLTIGIATGLGYCLTFLPTATILSQYFSR 148

  Fly   261 KRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLN-ACVCGALMRDPDWLIEEN 324
            :|:....:.::|....||.:|...:.| ::|..|..||::.||:.. ..:||||:|  ..:|:..
Zfish   149 RRSVVMAMASTGESFATFAFAPAFTAL-KNYIGRRYTLVVIGTLQGITIICGALLR--PIVIKPT 210

  Fly   325 RLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSE 389
            .|....|.:|    .::.:|:::....:|       ||:|
Zfish   211 SLTETEQKIT----YTLPVEQVQGFGSSG-------DSVV------------------------- 239

  Fly   390 IFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLM 454
                                   :||..::|                                |.
Zfish   240 -----------------------QSLEQEQG--------------------------------LK 249

  Fly   455 GGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAK 519
            .||..|..|
Zfish   250 SGIELEEVE-------------------------------------------------------- 258

  Fly   520 HTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVNSELAT 584
                                                          |..|.:.:|:
Zfish   259 ----------------------------------------------PVQINLKQQD--------- 268

  Fly   585 RRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRA 649
                                                                    ||.:.||
Zfish   269 --------------------------------------------------------NTSKNRL-- 275

  Fly   650 SSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFIIPYLYL 714
                                             .|.::..:..|..::...||..:.|..|.||:
Zfish   276 ---------------------------------LDLTVLKEGSFLCYSAFGLFATLGFFAPQLYV 307

  Fly   715 PDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMN---------INICYSLCMLVCGA 770
            .:.......:..::|.::|.:.|::.:|.:.:|::     ||         :.||.||..||.
Zfish   308 VELSASLGTERDKAAYMLSIMAISEIIGRLSIGWV-----MNCGCIRKIFVLLICVSLMCLVL-- 365

  Fly   771 SVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILV--SIVDLDDFTCAYGLVLLVQGVGMIA 833
             |.|  .::..:.||:|.||::||...:..|....:|.  .:|.:.....|.|:.:.:|....:|
Zfish   366 -VLF--TIVNGFWGLVVCCVLYGFLLGNITSTHIPMLAEDDVVGIQRMPLAVGVYVCIQSFAGLA 427

  Fly   834 GPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLI------EFCEKKAPKESDSDVLETKKA 890
            |||:.||:.:.|..:...||.....:.|..:...|:      ..|.::...|::|.|.:..||
Zfish   428 GPPLGGVLVDITQNYSAAFYSCAAGMGLGAIFLGLVRPAKTGHLCRRRNNGENNSAVEQVSKA 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	46/172 (27%)
		MFS	<685..869	CDD:119392	45/194 (23%)
slc16a6a	NP_001243761.1	MFS	31..464	CDD:119392	118/738 (16%)
		MFS_1	33..429	CDD:284993	107/701 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm25394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010