Protein Alignment chk and slc16a1b

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_956379.1
• Gene: slc16a1b / 368274
• ZFINID: ZDB-GENE-030515-5
• Length: 461
• Species: Danio rerio
• Alignment Length: 777
• Identity: 146/777 - (18%)
• Similarity: 226/777 - (29%)
• Gaps: 364/777 - (46%)

  Fly   129 TPKMPDGGYGWVVVFASLVVSLIADGLSFSF-GLINV---ELLEYFGESTSKTAWISSLFFSVPL 189
            ||  |:||:||.||    |.:.|:.|.|::| ..|.|   |:...|..::|:.:||||:..:|..
Zfish    12 TP--PEGGWGWAVV----VGAFISIGFSYAFPKSITVFFKEIEVIFNATSSQVSWISSIMLAVMY 70

  Fly   190 LMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSI 254
            ..|||.|.||:|:|.|.:.|.||.:|..|...:|||:::|.|....|:|.||||......|:..|
Zfish    71 AGGPISSILVNKFGSRPIMIAGGCLSGTGLVAASFCDTVEGLYFCVGVIGGLGLAFNLNPALTMI 135

  Fly   255 AFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDW 319
            ..:|.|:|..|.||..:|:.:.....|.|.|:|.:.:||||:.|||||.:||.||.|:|||
Zfish   136 GKYFYKRRPIANGIAMAGSPVFLSTLAPLNSWLFDQFGWRGSFLILGGALLNCCVAGSLMR---- 196

  Fly   320 LIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALK 384
                                                                      |:
Zfish   197 ----------------------------------------------------------PI----- 198

  Fly   385 RYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSP 449
                                                                |..|
Zfish   199 ----------------------------------------------------GPKP--------- 202

  Fly   450 DDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNEN 514
                ...|..|.||            :.|.||::..:|.||.|
Zfish   203 ----QPAIPKEDAE------------IKPQEKKTVMQTINGFL---------------------- 229

  Fly   515 IFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVN 579
                                                                             
Zfish   230 ----------------------------------------------------------------- 229

  Fly   580 SELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHR 644
                                                                             
Zfish   230 ----------------------------------------------------------------- 229

  Fly   645 YRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFII 709
                                                   |.:||....|.|:.|..:.:|.....
Zfish   230 ---------------------------------------DLTLFTHRGFLLYLLGNVIMFFGLFA 255

  Fly   710 PYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICY--SLCMLVCGASV 772
            |.::|.:|.|.......::|.|:|.:.....:....:|.:.:..|:...|.|  :..:|..|...
Zfish   256 PLVFLSNYAKSKHISKDKAAFLLSILAFTDMIARPSMGLVANTRWVRPRIQYFFAASVLYNGVCH 320

  Fly   773 FFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPI 837
            ...| |.|:|:|..:..|.||..|....|.....|:.:|....|:.|.|||.:|:...::.|||:
Zfish   321 LLAP-LSTDYLGFAIYAVFFGVAFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECAPVLLGPPL 384

  Fly   838 AGVIYEYTGRWDDTFYYAGIFIALSGV-------CSYLIEFCEKKAPKESDSDVLETKKAQL 892
            .|.:.:....:..|:...||.:.::.:       .:|.:...|||.         |.|:|:|
Zfish   385 LGRLNDIYDDYKYTYQGCGIVLVIASIFLFVGMGINYRLVDKEKKE---------EEKRAKL 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	68/175 (39%)
		MFS	<685..869	CDD:119392	45/192 (23%)
slc16a1b	NP_956379.1	2A0113	1..442	CDD:273325	146/777 (19%)
		MFS	20..415	CDD:119392	132/734 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm25394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.910