DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chk and CG10019

DIOPT Version :9

Sequence 1:	NP_001163063.1	Gene:	chk / 35578	FlyBaseID:	FBgn0033095	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_001368939.1	Gene:	CG10019 / 33600	FlyBaseID:	FBgn0031568	Length:	1159	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	94/428 - (21%)
Similarity:	176/428 - (41%)	Gaps:	81/428 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NNNHNGQNQSQNGG------ASNYQAL-PLTPAPANTPLHKAIKHD-LFPEVTFCNLSVEELADG 76
            ::....:|...|||      |:::.:| ..||.|:    |...:.| .||          .|||.
  Fly   361 HHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPS----HITDEEDSAFP----------GLADR 411

  Fly    77 AGHSRVVRSSVIELEDGTMTCLMNGNGQVKRRKRLISNESGDSIDSSSTEKKTPKMPDGGYGWVV 141
            ..|                  |::.|....||         ..:|  :|..:....||||:||::
  Fly   412 EFH------------------LLHRNIPALRR---------TGVD--TTRIRQYFYPDGGWGWII 447

  Fly   142 VFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRK 206
            ...|.:|.::..||..|:||:....::|. .:||....:.:|.:||.::......:|..|...|.
  Fly   448 CGVSFLVHILTTGLQLSYGLLWFYAVQYL-HNTSGIELLGALSWSVSMVATSFVVSLCRKRSIRL 511

  Fly   207 MTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGAS 271
            ::|:||:|...|...:||......::.::||:.|:|:.:....:.|.:..:|.::|.|...:..|
  Fly   512 LSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMVAMS 576

  Fly   272 GTGIGTFVYARLTSYLIESYGWR-GATLILGGTMLNACVCGALMRDPDWLIEENRLESRSQSVTT 335
            |.|:|..:::.:....:...||| |..::...|.|:..:  .||..|..|....|     :::..
  Fly   577 GEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFM--GLMYRPASLYHPQR-----RAIQH 634

  Fly   336 FSNSSVCLEEIKKLLDTGI------------TKEAVLDSLVTKNNTEANQQIDDP-----LDSAL 383
            ..|....:.|.|.:|...:            :.::|...::...::.|:..|..|     |::|.
  Fly   635 LKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKILLMTSSVASFGIYTPMFLMALNAAE 699

  Fly   384 K--RYRSEIFLPTFLSTQELDSICEVKSLSRRS--LRH 417
            :  ..:..:.|.|||.......:....:|.||.  :||
  Fly   700 QGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRH 737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	42/172 (24%)
chk	NP_001163063.1	MFS	<685..869	CDD:119392
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	67/302 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010