Protein Alignment chk and Mct1

DIOPT Version :10

• Sequence 1: NP_610230.3
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_477334.2
• Gene: Mct1 / 31198
• FlyBaseID: FBgn0023549
• Length: 626
• Species: Drosophila melanogaster
• Alignment Length: 788
• Identity: 235/788 - (29%)
• Similarity: 353/788 - (44%)
• Gaps: 183/788 - (23%)

  Fly   102 NGQVKRRKRLISNESGDSIDSSSTEKKTPKMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVEL 166
            :|...|||   |.:..::.:.....:.||  ||||:||||||.|.::.::.||:::|||:...|.
  Fly     3 HGPPARRK---SQQQHEACEMDMERQPTP--PDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEF 62

  Fly   167 LEYFGESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEML 231
            |:||.|....||||:|:...|....|||.|:.|::||||.:||.|.:::|....:|.|..::..|
  Fly    63 LDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTL 127

  Fly   232 MVTFGIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGA 296
            ::|.|..:|||.|:.|:.|:||:..:|:.||:.||||...|:|.||||:|.||.:||.:||||||
  Fly   128 IITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGA 192

  Fly   297 TLILGGTMLNACVCGALMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLD 361
            .||:||.:||..:.||:.|.         ||..:...|..:..|.     .||    ..|.|::|
  Fly   193 MLIIGGIVLNCIIFGAMFRP---------LELEAPPQTPPNTPST-----PKL----AKKSAIID 239

  Fly   362 SLVTKNNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSR-RSLRHKEGEEAPS 425
            ...|....|..:.:  |.|..|:       ||     |..|:.....:|.| .|:.|.      .
  Fly   240 QNTTAAELEPLKVL--PKDQYLQ-------LP-----QRTDTAVSGGALCRSNSVGHN------L 284

  Fly   426 RENLLSMSSGAG-------AYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRS 483
            :.||.:.|:||.       ..||...|..:.:|.:           |:|.:  |...|:|.....
  Fly   285 KPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDI-----------ARKCH--SQLQLTPLRDAH 336

  Fly   484 TGRTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCY 548
            ..|:.:|::...|..|                               .|..||..|.:|
  Fly   337 RERSASGTMYRPDALY-------------------------------QGSLHNLPDYVS------ 364

  Fly   549 YSKDETFALLEPSRRIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRR 613
                                                  :|.|       ||||...|   ..::|
  Fly   365 --------------------------------------SRND-------LSRSMSGS---GVIKR 381

  Fly   614 NISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDT 678
            ..|:|.||                   |..:.:..|..|..|      |.:||..||    |.:.
  Fly   382 YGSLRQSN-------------------NVSQSQEEAKCCGCI------TCSKETRDT----FAEM 417

  Fly   679 MKSIFDFSLFLDMKFALFNLSTLFLFIWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGM 743
            |    :|||..||.|.:|::|.....|.|.:||||:..|.:..|...:.::.|||.:|:|.|||.
  Fly   418 M----NFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGR 478

  Fly   744 IGLGYLGDLSWMNINICYSLCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILV 808
            |.|||:.|..|:|..:.|::|:..||.|...:| |..::..|...|.:||||..:....|..|||
  Fly   479 IILGYISDKPWVNRLLVYNVCLTACGVSTAMVP-LCHDFQSLAFYCCVFGFTIGAYVGLTSVILV 542

  Fly   809 SIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFCE 873
            .::.||..|.|:||:||.||:....||||.|.:|:.|..:...|..||:.||:||:..:.|...:
  Fly   543 DLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQ 607

  Fly   874 KKAPKESD 881
            :...::|:
  Fly   608 RLQVRKSE 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_610230.3	MFS_MCT_SLC16	138..>315	CDD:340910	81/176 (46%)
		MFS	<687..869	CDD:475125	70/181 (39%)
Mct1	NP_477334.2	MFS_MCT_SLC16	34..604	CDD:340910	222/739 (30%)