Protein Alignment chk and Slc16a12

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001178566.1
• Gene: Slc16a12 / 309525
• RGDID: 1311468
• Length: 486
• Species: Rattus norvegicus
• Alignment Length: 736
• Identity: 141/736 - (19%)
• Similarity: 231/736 - (31%)
• Gaps: 327/736 - (44%)

  Fly   133 PDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIWSN 197
            ||||:||::|....:|::....::....:..||...||.:..|:||||.|:...:.:|..|:.|.
  Rat    13 PDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSV 77

  Fly   198 LVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDKKR 262
            :.::..|:...:|||::::.|..|.||..|::.|.::.|:::|||..:.|..|:..:..:|.:::
  Rat    78 VSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRK 142

  Fly   263 TFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDWLIEENRLE 327
            .||.||..||:|||||:.|.:...|||.:.||||.|||||.:||.||||||||
  Rat   143 AFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMR------------ 195

  Fly   328 SRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSEIFL 392
                        .:.|:|                               ||
  Rat   196 ------------PITLKE-------------------------------DP-------------- 203

  Fly   393 PTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLMGGI 457
                |..|       ||..|.:.|
  Rat   204 ----SGPE-------KSHDRDAQR----------------------------------------- 216

  Fly   458 AHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAKHTT 522
                 |:.|:|     ...||                     ||::...:|
  Rat   217 -----EDCKQA-----SPYSP---------------------LTKEWTETR-------------- 236

  Fly   523 PSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVNSELATRRA 587
                                  :.|...:...|.|:
  Rat   237 ----------------------LCCSLQQGYGFLLM----------------------------- 250

  Fly   588 RLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSC 652
                                            |:|:
  Rat   251 --------------------------------SDFV----------------------------- 254

  Fly   653 PNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFIIPYLYLPDY 717
                                             .|.:.:.|..:..|.||:   :::||
  Rat   255 ---------------------------------VLAVSVLFMAYGCSPLFV---YLVPY------ 277

  Fly   718 MKQYKYDVS--QSAELISDVGIAQTVGMIGLGYLGDLSWM-NIN-ICYSLCMLVCGASVFFMPLL 778
              .....||  |:|.|:|.:|:...||.|..|:|.|...: |.. :||...:.:.|.....:|:|
  Rat   278 --ALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPML 340

  Fly   779 ITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYE 843
             .::..|:.....||:...:..:..|.:...||.....:.|.|:|..:..|..:..|||||.:.:
  Rat   341 -QSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVD 404

  Fly   844 YTGRWDDTFYYAGIFIALSGV 864
            .||.:...|...|..:..|.:
  Rat   405 TTGSYTAAFLLCGFAMIFSSI 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	63/171 (37%)
		MFS	<685..869	CDD:119392	46/184 (25%)
Slc16a12	NP_001178566.1	2A0111	12..451	CDD:331689	141/736 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..221		10/121 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2764
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm12325
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860