Protein Alignment chk and Slc16a6

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_006247682.2
• Gene: Slc16a6 / 303772
• RGDID: 735117
• Length: 606
• Species: Rattus norvegicus
• Alignment Length: 814
• Identity: 156/814 - (19%)
• Similarity: 263/814 - (32%)
• Gaps: 343/814 - (42%)

  Fly   115 ESGDSIDSSSTEKKT---------PKMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYF 170
            |:|.| .|..|:|.:         .::||||:||||..:...:.:...|:..|||:...:|::.|
  Rat    77 ETGCS-RSRMTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSF 140

  Fly   171 GESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTF 235
            .||.||.:||.|:...:.....|:.:.|.:::|.|.:.:.||::.:.|...:||...:..:.::.
  Rat   141 DESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISI 205

  Fly   236 GIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLIL 300
            ||:||||....::..|..::.:|||:|:..|.:.::|.....|.:|...:.|.|..|||.:.|.:
  Rat   206 GIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFV 270

  Fly   301 GGTMLNACVCGALMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVT 365
            |...||..|||||:|
  Rat   271 GLLQLNVMVCGALLR-------------------------------------------------- 285

  Fly   366 KNNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLL 430
                                       |..:                         :.|
  Rat   286 ---------------------------PIII-------------------------KGP------ 292

  Fly   431 SMSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSS 495
                            |||.     .|..|...|        ::.:..:||..|      |:.|.
  Rat   293 ----------------GSPK-----AIPLEPRRE--------VQYMLENEKTRT------SIDSI 322

  Fly   496 DEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEP 560
            |.|.                    ..|.|..|:.....|...|.:
  Rat   323 DSGV--------------------ELTTSPKNVPSEAKREQEVRV-------------------- 347

  Fly   561 SRRIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKD 625
                        ||:|::             :.|         |.|.:.
  Rat   348 ------------EQQQTL-------------VVG---------PKHSQK---------------- 362

  Fly   626 MRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLD 690
                                  ||                               .:.|||:..|
  Rat   363 ----------------------RA-------------------------------PLLDFSILKD 374

  Fly   691 MKFALFNLSTLFLFIWFIIPYLYL----------PDYMKQYKYDVSQSAELISDVGIAQTVGMIG 745
            ..|..:.|..||..:.|..|.||:          ||          ::|.|:|.:.||:..|.||
  Rat   375 RSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPD----------RAAFLLSTMAIAEVFGRIG 429

  Fly   746 LGYLGDLSWMNINICY--SLCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILV 808
            :|.:  |:...|...|  .:|:::...|:|.. ...|.:.|||:..|.|| :...:...|...|:
  Rat   430 MGLV--LNREPIRKIYIELICVILLTVSLFAF-TFATEFWGLMLCSVFFG-SMVGTIGGTHIPLL 490

  Fly   809 S---IVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIE 870
            :   :|.::..:.|.|:.:.:|.:..:||||:||::.:.:..:...||.....:||:.||..|:.
  Rat   491 AEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVR 555

  Fly   871 FCEK------------------KAPKESDSDVLE 886
            .|:|                  ||.::...|.||
  Rat   556 PCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	51/171 (30%)
		MFS	<685..869	CDD:119392	53/198 (27%)
Slc16a6	XP_006247682.2	MFS_MCT7	108..555	CDD:340980	139/746 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm12325
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910