Protein Alignment chk and Slc16a13

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001005530.1
• Gene: Slc16a13 / 287451
• RGDID: 1359138
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 766
• Identity: 134/766 - (17%)
• Similarity: 228/766 - (29%)
• Gaps: 362/766 - (47%)

  Fly   133 PDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIWSN 197
            ||||:||:||.::...|.:..|:..|||:..||.:..|.|..::.:||:|:..:|.....||.|.
  Rat     8 PDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSA 72

  Fly   198 LVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDKKR 262
            |..|.|.|.:.:.||:::|.|..|:||..|:..|.::.|::||.|..:.:...:..::.:|.::|
  Rat    73 LSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTLACLSRYFSQRR 137

  Fly   263 TFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDWLIEENRLE 327
            :.|.|:..:|.||.:|.:|.|..:|:.:|.||||.|::....|:...||||:|
  Rat   138 SLAMGLALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLR------------ 190

  Fly   328 SRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSEIFL 392
                                                              ||
  Rat   191 --------------------------------------------------PL------------- 192

  Fly   393 PTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLMGGI 457
                            ||:                                      :||.:||
  Rat   193 ----------------SLT--------------------------------------EDTAVGG- 202

  Fly   458 AHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAKHTT 522
                                          |...:.|
  Rat   203 ------------------------------PWAQITS---------------------------- 209

  Fly   523 PSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVNSELATRRA 587
                                  :.|
  Rat   210 ----------------------LLC---------------------------------------- 212

  Fly   588 RLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSC 652
                               |...||..:::                    .::||
  Rat   213 -------------------HGPFLRYTVAL--------------------TLINT---------- 228

  Fly   653 PNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFIIPYLYLPDY 717
                                                                 .:.|||::|..:
  Rat   229 -----------------------------------------------------GYFIPYVHLVAH 240

  Fly   718 MKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICYSLCMLVCGASVFFMPLLITNY 782
            ::...:|...:|.|:|...|:..||.:..|:|||.....:.....|...:.|.|:...|:...:
  Rat   241 LQDLGWDPLPAAFLLSVAAISDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQAS- 304

  Fly   783 MGLMVMCVIFGFTFASSFSFTP---SILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEY 844
            ..|:|:.|.:|||   |.:.||   |::..:|......|..|||.:::.||.:.|.|::|.:.:.
  Rat   305 TTLVVLAVAYGFT---SGALTPVAFSVIPELVGTGRIYCGLGLVQMIESVGGLLGAPLSGYLRDV 366

  Fly   845 TGRWDDTFYYAGIF-IALSGVCSYLIEF--CEKKAPKESDSDVLETKKAQL 892
            ||.:..:|..||.| :|.|||...|..|  |...:.......|:|....::
  Rat   367 TGNYTASFVVAGAFLLAGSGVLITLPHFFSCISLSTSRPQDLVIEAPDTKI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	55/171 (32%)
		MFS	<685..869	CDD:119392	49/187 (26%)
Slc16a13	NP_001005530.1	MFS_MCT11_13	13..392	CDD:340981	125/734 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm12325
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.910