DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chk and Slc16a11

DIOPT Version :9

Sequence 1:	NP_001163063.1	Gene:	chk / 35578	FlyBaseID:	FBgn0033095	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	XP_038941393.1	Gene:	Slc16a11 / 287450	RGDID:	1311125	Length:	593	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	70/217 - (32%)
Similarity:	120/217 - (55%)	Gaps:	16/217 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 GDSIDSSSTEKKTPKM----------PDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFG 171
            |..:::|.|....|:.          ||||:||||..|:..|:.::.||..|.||...:|.|:|.
  Rat   129 GPGVETSFTGVSPPQQTAMTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFE 193

  Fly   172 ESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFG 236
            .|...|||:|:|..:|.....|:.|.|..::|.|.:.::|||:::.|...|:|..|:..|.:..|
  Rat   194 RSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLG 258

  Fly   237 IISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILG 301
            :::|.|..:.:..|:.:::.:|.::|..|.|:..:|.|..:.:.|....:|::::|||||.|:||
  Rat   259 LLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLG 323

  Fly   302 GTMLNACVCGALMR------DP 317
            ...|:...||||:|      ||
  Rat   324 AVTLHLTPCGALLRPLALSGDP 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	55/171 (32%)
chk	NP_001163063.1	MFS	<685..869	CDD:119392
Slc16a11	XP_038941393.1	PHA03378	<42..158	CDD:223065	6/28 (21%)
Slc16a11	XP_038941393.1	MFS_MCT11_13	160..549	CDD:340981	62/186 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.910