Protein Alignment chk and SLC16A9

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_016871372.1
• Gene: SLC16A9 / 220963
• HGNCID: 23520
• Length: 551
• Species: Homo sapiens
• Alignment Length: 820
• Identity: 171/820 - (20%)
• Similarity: 267/820 - (32%)
• Gaps: 345/820 - (42%)

  Fly   131 KMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIW 195
            |.||||:|||:||.|.:...:..|...:.|::.:|.|:.|||...||||:.||...|.||..|:.
Human     5 KSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPVC 69

  Fly   196 SNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDK 260
            |..|..:|.|.:||..|.:.|.|..||||..:|..|..::||:.|||.|:.|...|.....:||.
Human    70 SLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDD 134

  Fly   261 KRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDWLIEENR 325
            :|..|.|:.::|:.:|.|:||.|...|:|.||..|..||:|...||...||:|||
Human   135 RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMR---------- 189

  Fly   326 LESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSEI 390
                                                                ||.|      |:.
Human   190 ----------------------------------------------------PLQS------SDC 196

  Fly   391 FLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLMG 455
            .||..::.::|                                               ||
Human   197 PLPKKIAPEDL-----------------------------------------------PD----- 209

  Fly   456 GIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAKH 520
                                                                :|
Human   210 ----------------------------------------------------KY----------- 211

  Fly   521 TTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVNSELATR 585
               ||.|.|...|..| ::||.:.    ||.:|
Human   212 ---SIYNEKGKNLEEN-INILDKS----YSSEE-------------------------------- 236

  Fly   586 RARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRAS 650
                                      :..|::.|.::.:|..:|:|.       ..||      :
Human   237 --------------------------KCRITLANGDWKQDSLLHKNP-------TVTH------T 262

  Fly   651 SCPNIYRNSMT-------TIAKEEEDTW--YDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIW 706
            ..|..|:..:.       .:||.:   |  |.|:.....::|...:|          |.||:.|.
Human   263 KEPETYKKKVAEQTYFCKQLAKRK---WQLYKNYCGETVALFKNKVF----------SALFIAIL 314

  Fly   707 FIIPYLYLPDYMKQYKYDVSQSAE---------LISDVGIAQTVGMIGLGYLGDLSWMNINICYS 762
            ......:.|..:.:   ||::|:.         |||.:||...||.:.||.|.|..|:|....|.
Human   315 LFDIGGFPPSLLME---DVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADFKWINTLYLYV 376

  Fly   763 LCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQ 827
            ..:::.|.::..:| ...:|:.|.::..|.|| ...::|..|.:....|.::....|||:::...
Human   377 ATLIIMGLALCAIP-FAKSYVTLALLSGILGF-LTGNWSIFPYVTTKTVGIEKLAHAYGILMFFA 439

  Fly   828 GVGMIAGPPIAGVI------------------------------------------YEYTGRWDD 850
            |:|...||||.|.|                                          |::|..:|.
Human   440 GLGNSLGPPIVGKIFILKSSHFTVLPCHISRYRGPDCNSSTDLYKRNLHGTSHGWFYDWTQTYDI 504

  Fly   851 TFYYAGIFIALSGVCSYLI-----EFCEKKAPKESDSDVL 885
            .||::|..:.|.|....|.     :.|.|:.||.:.:..|
Human   505 AFYFSGFCVLLGGFILLLAALPSWDTCNKQLPKPAPTTFL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	66/171 (39%)
		MFS	<685..869	CDD:119392	52/234 (22%)
SLC16A9	XP_016871372.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm8605
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810