DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chk and Slc16a11

DIOPT Version :9

Sequence 1:	NP_001163063.1	Gene:	chk / 35578	FlyBaseID:	FBgn0033095	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_694721.2	Gene:	Slc16a11 / 216867	MGIID:	2663709	Length:	447	Species:	Mus musculus

Alignment Length:	198	Identity:	69/198 - (34%)
Similarity:	115/198 - (58%)	Gaps:	9/198 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 TPK---MPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLL 190
            |||   .||||:||||..|:..|:.::.||..|.||...:|.|:|..|...|||:|:|..:|...
Mouse     2 TPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQA 66

  Fly   191 MGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIA 255
            ..|:.|.|..::|.|.:.::|||:::.|...|:|..|:..|.:..|:::|.|..:.:..|:.:::
Mouse    67 ASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLS 131

  Fly   256 FWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMR----- 315
            .:|.::|..|.|:..:|.|..:.:.|....:|::::|||||.|:||...|:...||||:|
Mouse   132 RYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALS 196

  Fly   316 -DP 317
             ||
Mouse   197 GDP 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	55/171 (32%)
chk	NP_001163063.1	MFS	<685..869	CDD:119392
Slc16a11	NP_694721.2	MFS	14..403	CDD:391944	62/186 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010