DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chk and slcf-1

DIOPT Version :9

Sequence 1:	NP_001163063.1	Gene:	chk / 35578	FlyBaseID:	FBgn0033095	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_509762.2	Gene:	slcf-1 / 186633	WormBaseID:	WBGene00010340	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	58/228 - (25%)
Similarity:	92/228 - (40%)	Gaps:	50/228 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 GWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKT-----AWISSLFFSVP----LLMGP 193
            |:.::||...|..:.:|               |.|...||     ....:....||    |::||
Worm    43 GFYILFAETGVRQVMNG---------------FVEPVIKTYNCTKDQADTAVLVVPMASSLILGP 92

  Fly   194 IWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMV-TFGIISGLGLGIGYV-TAVVSI-A 255
            ..|....:.|.|...|.|..::...|.:..||.:|.:||: ||    |:|:|.|.: .:::|| .
Worm    93 FCSIFYQRSGARISIIAGSFLTGGSFVVGPFCKNIYLLMLATF----GMGIGCGLMRNSIISIQC 153

  Fly   256 FWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESY-GWRGATLILGGTMLNACVCGALMRDPDW 319
            .:|.|||.......:.|.|:|.|:..|...:::..| .|..|...|....:.:.:.|..:..|.
Worm   154 EYFKKKRNTVMAAISIGPGLGIFILPRTLKFIMVKYNSWGPAWWFLSLFYIVSAIMGLFITKPP- 217

  Fly   320 LIEENRLESRSQSVTTFSNSS---VCLEEIKKL 349
                      |:..:|||..|   ||    |||
Worm   218 ----------SEQTSTFSFGSAFKVC----KKL 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	46/184 (25%)
chk	NP_001163063.1	MFS	<685..869	CDD:119392
slcf-1	NP_509762.2	MFS	44..410	CDD:119392	57/227 (25%)
slcf-1	NP_509762.2	MFS_1	79..376	CDD:284993	49/177 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900