Protein Alignment chk and mct-3

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_510308.1
• Gene: mct-3 / 181497
• WormBaseID: WBGene00010834
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 796
• Identity: 185/796 - (23%)
• Similarity: 302/796 - (37%)
• Gaps: 256/796 - (32%)

  Fly   121 DSSSTEKKTPKM-----PDGGYGWVVVFASLVVSLIADGLSFSFG-LINVELLEYFGESTSKTAW 179
            |..:.||:....     |||||||.:|.||.::::|.||:.|:.| ::....:..||.|.:..|.
 Worm    17 DPETVEKELEDAGFIAPPDGGYGWAIVAASFLLNMIVDGVIFTVGKILQPAWVHSFGISEASAAM 81

  Fly   180 ISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLG 244
            ..|:........|||.|.|.:.:|||::.:.|.:::|.||.||....:|.:|.|:||:|:|.|.|
 Worm    82 TMSILSGCYFFAGPIASVLCNVFGCRQVALAGSLIAALGFLLSISAPNIYVLYVSFGLIAGAGFG 146

  Fly   245 IGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYG--WR-----GATLILGG 302
            :.|:.|:|.|:.:|.|||:.||||...|:||||.|:|.|...:.:..|  |:     .|.:.:.|
 Worm   147 MMYLPAIVIISQYFAKKRSVATGIAVCGSGIGTTVFALLNDVVWDFVGGDWKQFLVYTAAVTISG 211

  Fly   303 TMLNACVCGALMR--DPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLL-DTGITKEAVLDS-L 363
              |.||:   |:|  .|          |:.|           :|::.|:| |....||.|.:| |
 Worm   212 --LGACI---LLRPLKP----------SKDQ-----------IEKVAKVLEDYEEHKEKVPESPL 250

  Fly   364 VTKNNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSREN 428
            ::|:||                        .|||:.||
 Worm   251 LSKHNT------------------------PFLSSLEL--------------------------- 264

  Fly   429 LLSMSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLR 493
                                          |.|                       |:..||
 Worm   265 ------------------------------HTA-----------------------GKLENG--- 273

  Fly   494 SSDEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALL 558
                                      |.|.||.::         ||.:|:::
 Worm   274 --------------------------HHTGSIKSI---------VDAVSKEI------------- 290

  Fly   559 EPSRRIRPTVIAIPEQEQSVNSELATRRARLD-----SITGIRRLSRSKKPSHHRSNLRRNISIR 618
                             :.:|..|    .|.|     |.|.|...||:       ..:.|
 Worm   291 -----------------EDLNKPL----LRKDIFYSGSTTNIAARSRT-------GTMTR----- 322

  Fly   619 NSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIF 683
                 ::...|:.|:.:||.:....:|..:|..  |...|....||.|.:   .......:|.:.
 Worm   323 -----EEAAEHQQSLRFRGKVETPQQYLSKADL--NAGDNGDVAIANESK---IQEIKQALKQLV 377

  Fly   684 DFSLFLDMKFALFNLSTLFLFIWFIIPYLYLPDYMKQYK-YDVSQSAELISDVGIAQTVGMIGLG 747
            |..|.....|.|...|.......|.:|::||.:::.:.: ...::.:..:|.:|:...|..||.|
 Worm   378 DKELLFSPSFLLLAFSGTLTLCCFYVPFIYLGNHLDKIEGLTTAEKSFTVSLIGVLNIVARIGCG 442

  Fly   748 YLGD---LSWMNINICYSLCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVS 809
            .|.|   :|.:.:|   :..::..|.:...:| |.|.|...:..||.|....|...:....|:|.
 Worm   443 ILADRPEVSALAVN---NFALIAAGLATMTVP-LYTAYWQFLAFCVPFSIGVACFAALRSIIVVE 503

  Fly   810 IVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFCEK 874
            ::.|:..:.|:|::|...|||.:.|.|:|..:.:|||.:|.:||..|..:.:||.....:....|
 Worm   504 LIGLEKLSNAFGILLTFMGVGAVVGSPLAAAMKDYTGNFDTSFYVMGALMTISGAMCIPLGGLRK 568

  Fly   875 KAPKESDSDVLETKKA 890
            :....|||.  :.|||
 Worm   569 RELARSDSS--DAKKA 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	63/179 (35%)
		MFS	<685..869	CDD:119392	48/187 (26%)
mct-3	NP_510308.1	MFS_MCT_SLC16	39..563	CDD:340910	170/751 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4139
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840