Protein Alignment chk and Slc16a10

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_620186.1
• Gene: Slc16a10 / 170566
• RGDID: 69197
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 795
• Identity: 134/795 - (16%)
• Similarity: 228/795 - (28%)
• Gaps: 354/795 - (44%)

  Fly   112 ISNESGDSID----SSSTEKKTPKMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGE 172
            :|:.|.:.::    .|:..::.|:.|:||:||:|:.|::..:....|:..::|::.|.:||.||.
  Rat    39 VSDGSVEKVEVELTRSTGNQEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGA 103

  Fly   173 STS-----KTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLM 232
            ...     |.||:.||...:.....||.|...|.:|||:..:||..|...|...|||.:|||.|.
  Rat   104 KDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLY 168

  Fly   233 VTFGIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGAT 297
            .|:|::...|....|..::|.:..:|.|:.....||..:|:.:.|.:                ..
  Rat   169 FTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTIL----------------LP 217

  Fly   298 LILGGTMLNACVCGALMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDS 362
            |:||.......:|..|           |:              :|:
  Rat   218 LLLGNLTSTVGLCYTL-----------RI--------------LCI------------------- 238

  Fly   363 LVTKNNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRE 427
                                   :...:||..|
  Rat   239 -----------------------FMFVLFLAGF-------------------------------- 248

  Fly   428 NLLSMSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSL 492
                      .|.|                                  |.||.|...
  Rat   249 ----------TYRP----------------------------------LVPSSKEKE-------- 261

  Fly   493 RSSDEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFAL 557
                                                             |||     |:...|
  Rat   262 -------------------------------------------------SED-----SRSSFF-- 270

  Fly   558 LEPSRRIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNF 622
               ||                                 |:||..||
  Rat   271 ---SR---------------------------------RKLSPPKK------------------- 280

  Fly   623 LKDMRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSL 687
                                                                       ||:|:|
  Rat   281 -----------------------------------------------------------IFNFAL 286

  Fly   688 FLDMKFALFNLSTLFLFIWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLG----Y 748
            |.:..:|::..........:.:||::|.:::|:...||:....|...:|:...||.:..|    |
  Rat   287 FKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADY 351

  Fly   749 LGDLSWMNINICYSLCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDL 813
            |..:..:.:.:   |.....|.:...:| |.:.:..|:.:|:|.|.......|....|...:|..
  Rat   352 LPGVKKVYLQV---LSFFFIGLTSMMIP-LCSVFGALIALCLIMGLFDGCFISIMAPIAFELVGP 412

  Fly   814 DDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFCEKKAPK 878
            .|.:.|.|.:|....:.|..|||:||::::..|.:|..||.|||...:.|....||.:...|..:
  Rat   413 QDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQR 477

  Fly   879 ESDSDVLETKKAQLL 893
            |...:....|..::|
  Rat   478 EISKNTGGEKMEKML 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	47/176 (27%)
		MFS	<685..869	CDD:119392	46/187 (25%)
Slc16a10	NP_620186.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64		4/24 (17%)
		2A0113	60..481	CDD:273325	129/761 (17%)
		MFS	70..469	CDD:119392	121/739 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810