Protein Alignment chk and slc16a2

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_031747020.1
• Gene: slc16a2 / 100494635
• XenbaseID: XB-GENE-980579
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 740
• Identity: 127/740 - (17%)
• Similarity: 201/740 - (27%)
• Gaps: 356/740 - (48%)

  Fly   131 KMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTS--------KTAWISSLFFSV 187
            ::|:||:|||||.|:...|....|:..|||:|.|.|.   ||...        ||||:.||...:
 Frog    50 RVPEGGFGWVVVLAATWCSGSIFGIQNSFGIIYVMLQ---GEMDGTEEQGMDFKTAWVGSLAMGM 111

  Fly   188 PLLMGPIWSNLVDKYGCRKMTILGGVVSAF-GFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAV 251
            .....|:.|...|:.|||| |..||...|| |...|||..|:.:...|:||:.|.|....:..::
 Frog   112 IFFCSPVVSIFTDRLGCRK-TSSGGAALAFIGLLSSSFTKSLGVRYFTYGILFGCGCSFAFQPSL 175

  Fly   252 VSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRD 316
            |.:..:|.|:.....||.|.|                                  :||
 Frog   176 VILGHYFKKRLGLVNGIVAGG----------------------------------SCV------- 199

  Fly   317 PDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDS 381
                                  .::||..:.|
 Frog   200 ----------------------FTMCLPFLLK--------------------------------- 209

  Fly   382 ALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVI 446
                                                                             
 Frog   210 ----------------------------------------------------------------- 209

  Fly   447 GSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSL 511
                  :|||..
 Frog   210 ------MMGGAI----------------------------------------------------- 215

  Fly   512 NENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQ 576
                                ||:| :..:||..|........||..|.|     |.|....|:|:
 Frog   216 --------------------GLQH-TFQVLSVFMFIQIFLSLTFKPLLP-----PPVDFSKEKEK 254

  Fly   577 SVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLN 641
                           :.|     |||.                                :..|.:
 Frog   255 ---------------VAG-----RSKA--------------------------------QQCMAH 267

  Fly   642 THRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIW 706
            |.:|                                     |:..:|....:.::.|......:.
 Frog   268 TRKY-------------------------------------FNMQVFRRKTYTIWALGIATTVLG 295

  Fly   707 FIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGD----LSWMNINICYSLCMLV 767
            :.:||::|..:::|...:.::...|:..:|....:|.:..|.:||    |..:.:.:.   ..|:
 Frog   296 YFVPYVHLIKFVEQRFKENTKEWVLLVCIGATSGIGRLASGRIGDSIPGLKKIYLQVA---SFLL 357

  Fly   768 CGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVGMI 832
            .|.....:||... :..::|:|:..|.......|....|...:|.....:.|.|.||.:..:.|.
 Frog   358 LGILSMMLPLCQV-FESVIVVCLFLGLCDGFLISMMSPIAFELVGPMQASQAIGYVLGLMSIPMT 421

  Fly   833 AGPPIAGVIYEYTGRWDDTFYYAGI 857
            |||||||::.:|.|.:|..||.|||
 Frog   422 AGPPIAGLLRDYCGSYDLAFYLAGI 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	48/180 (27%)
		MFS	<685..869	CDD:119392	43/177 (24%)
slc16a2	XP_031747020.1	MFS_MCT8	57..459	CDD:341023	124/733 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910