Protein Alignment chk and slc16a14

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_002944264.2
• Gene: slc16a14 / 100491705
• XenbaseID: XB-GENE-6049356
• Length: 513
• Species: Xenopus tropicalis
• Alignment Length: 769
• Identity: 178/769 - (23%)
• Similarity: 283/769 - (36%)
• Gaps: 285/769 - (37%)

  Fly   118 DSIDSSSTEKKTPKMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISS 182
            |:...:..:|..|.: |.|:.|:||.:|.:|.|:..|...:.|::|:|.||.|.:|...||||||
 Frog    15 DTKSKTQMKKVNPNI-DRGWAWMVVLSSFLVHLLVMGSQMALGILNLEWLEEFKQSRGLTAWISS 78

  Fly   183 LFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGY 247
            |...:.|::|||....::..||||..::||.:::.|:.||::..::..|..:||:.:|:|.|:.|
 Frog    79 LSMGITLIVGPIIGLFINTCGCRKTAMIGGFLTSLGWVLSAYAPNVHFLFFSFGVTAGIGSGMVY 143

  Fly   248 VTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGA 312
            :.|||::..:|.|:|..|.|:..:|||.|||:...|..||....|||.|.:|.|...||.|||||
 Frog   144 LPAVVTVGHYFQKRRALAQGLSTTGTGFGTFLITVLLKYLCRELGWRNAMIIQGAVTLNLCVCGA 208

  Fly   313 LMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDD 377
            |||
 Frog   209 LMR-------------------------------------------------------------- 211

  Fly   378 PLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPS 442
            |||                                    |.| |.....|
 Frog   212 PLD------------------------------------HDE-EHLKDHE--------------- 224

  Fly   443 TAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASS 507
                             |||.:.|.|                           .||.|
 Frog   225 -----------------EAAVDPKDA---------------------------KEGAL------- 238

  Fly   508 RYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIP 572
                                |.||.::.||      ::|                         .
 Frog   239 --------------------LNVNAIKANS------ELH-------------------------E 252

  Fly   573 EQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRG 637
            |:|...:::.|              :|.||:.:            ||..|:.||    |.:....
 Frog   253 EEEGKASADTA--------------VSWSKEET------------RNDIFINDM----NKLSIMK 287

  Fly   638 AMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLF 702
            .:  ||                ||...:.....||.::....      |||.:..|..|....|.
 Frog   288 TL--TH----------------MTVSVRSGFFAWYSSYFGAS------SLFTNKVFVAFVFWALL 328

  Fly   703 LFIWFIIPYLYLPDYMKQYKY-DVSQSAELISDVGIAQTVGMIGLGYLGDL----SWMNINICYS 762
            .:..|:||:::||:.::.|.. :.:....|.|.:.|....|.:.||:||||    :| |:.|..:
 Frog   329 AYCSFVIPFIHLPEIVEMYGLTEQNNIFPLTSIIAIVHIFGKVILGFLGDLPCVSAW-NVFIASN 392

  Fly   763 LCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQ 827
            ..:   |.|:..:||:.. |..|.::|.:.||: :..||..|.:...:|.:.....|||:::...
 Frog   393 FTL---GVSILILPLMHV-YSSLALVCALIGFS-SGYFSLMPVVTEDLVGIKQLANAYGIIICAN 452

  Fly   828 GVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFC--EKKAPKE 879
            |:..:.|||.||.||:.|.::|.:||..|: :.:.|:...|:|.|  .|..|.:
 Frog   453 GISALLGPPFAGWIYDITQKYDYSFYVCGL-LYMVGIICLLLEPCLQSKDQPSK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	69/171 (40%)
		MFS	<685..869	CDD:119392	55/188 (29%)
slc16a14	XP_002944264.2	MFS_MCT14	34..495	CDD:340987	169/737 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2724
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm14090
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960