Protein Alignment chk and LOC100491288

DIOPT Version :10

• Sequence 1: NP_610230.3
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_031757084.1
• Gene: LOC100491288 / 100491288
• XenbaseID: XB-GENE-29080603
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 148/779 - (18%)
• Similarity: 238/779 - (30%)
• Gaps: 342/779 - (43%)

  Fly   129 TPKMPDGGYGWVVVFASLVVSLIADGLSFSFG-LINV---ELLEYFGESTSKTAWISSLFFSVPL 189
            ||  ||||:||:||..    :.|:.|.|::|. .|.|   |:.|:||.|.|:.|||||:..:...
 Frog    12 TP--PDGGWGWMVVLG----AFISMGFSYAFSKAITVFFKEIQEHFGASYSEIAWISSILLAAMY 70

  Fly   190 LMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSI 254
            ..||:.|.||::||.|.:.|.||::|..|..:::|.:||..|.:..|:|:|.|..:....:|:.:
 Frog    71 AGGPVSSILVNRYGSRPVVIFGGLLSGVGMIIATFSSSILQLYIFIGVIAGFGFSLNLQPSVIVV 135

  Fly   255 AFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDW 319
            ..:|.|||..|.|:..:|:.:.....|.|..:|.:.:||||:..|||..:||.||.|||.|
 Frog   136 GKYFLKKRPIANGLAMAGSPVVLSTLAPLNQFLFDKFGWRGSFFILGALLLNCCVAGALFR---- 196

  Fly   320 LIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALK 384
                                                                             
 Frog   197 ----------------------------------------------------------------- 196

  Fly   385 RYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSP 449
                                                                             
 Frog   197 ----------------------------------------------------------------- 196

  Fly   450 DDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNEN 514
                                     .:.||
 Frog   197 -------------------------PIGPS----------------------------------- 201

  Fly   515 IFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVN 579
                  ||..|
 Frog   202 ------TTDKI------------------------------------------------------ 206

  Fly   580 SELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHR 644
                                 .|||:                  :|:           |...|:.
 Frog   207 ---------------------QKKPA------------------QDL-----------AEKGTNE 221

  Fly   645 YRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFII 709
            ..|.|:..|..|...|       |:|..:..:.....:.|.:||....|.::.:..:.:|..|..
 Frog   222 TLLTANKLPPSYGTKM-------EETKQETCLQKFNKVLDLTLFKHRGFMIYLVGNVVMFFAFYA 279

  Fly   710 PYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICY---------SLCM 765
            |.::|..|.|....|...:|.|:|.:.|.......|.|.:.:..|:...|.|         ..|.
 Frog   280 PIVFLTPYAKHLGVDEYSAAFLLSILAIVDMFARPGTGLIANTKWVRPKIQYFFSFSVTFNGFCH 344

  Fly   766 LVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVG 830
            |:|.        ..|.|:||:|..|.||..|....:.....|:.:|.:..|:.|.|||.:|:.|.
 Frog   345 LMCP--------FATGYVGLVVYSVFFGLAFGMVCALLFETLMDLVGVKRFSSAVGLVTIVECVP 401

  Fly   831 MIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFCE----KKAPKESDSDVLETKKA 890
            ::.||||.|.|.:..|.:...::..|..:.|:|:..:::.:..    :|..||..:..:|.|::
 Frog   402 LLLGPPIGGAIVDAFGDYKYMYFECGAIMVLAGLFLFVMNYYNYRMLEKEEKEKQAKEMEMKES 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_610230.3	MFS_MCT_SLC16	138..>315	CDD:340910	67/180 (37%)
		MFS	<687..869	CDD:475125	50/190 (26%)
LOC100491288	XP_031757084.1	2A0113	10..448	CDD:273325	143/760 (19%)