Protein Alignment chk and LOC100491288

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_031757084.1
• Gene: LOC100491288 / 100491288
• -ID: -
• Length: 497
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 148/779 - (18%)
• Similarity: 238/779 - (30%)
• Gaps: 342/779 - (43%)

  Fly   129 TPKMPDGGYGWVVVFASLVVSLIADGLSFSFG-LINV---ELLEYFGESTSKTAWISSLFFSVPL 189
            ||  ||||:||:||..    :.|:.|.|::|. .|.|   |:.|:||.|.|:.|||||:..:...
 Frog    12 TP--PDGGWGWMVVLG----AFISMGFSYAFSKAITVFFKEIQEHFGASYSEIAWISSILLAAMY 70

  Fly   190 LMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSI 254
            ..||:.|.||::||.|.:.|.||::|..|..:::|.:||..|.:..|:|:|.|..:....:|:.:
 Frog    71 AGGPVSSILVNRYGSRPVVIFGGLLSGVGMIIATFSSSILQLYIFIGVIAGFGFSLNLQPSVIVV 135

  Fly   255 AFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDW 319
            ..:|.|||..|.|:..:|:.:.....|.|..:|.:.:||||:..|||..:||.||.|||.|
 Frog   136 GKYFLKKRPIANGLAMAGSPVVLSTLAPLNQFLFDKFGWRGSFFILGALLLNCCVAGALFR---- 196

  Fly   320 LIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALK 384
                                                                             
 Frog   197 ----------------------------------------------------------------- 196

  Fly   385 RYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSP 449
                                                                             
 Frog   197 ----------------------------------------------------------------- 196

  Fly   450 DDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNEN 514
                                     .:.||
 Frog   197 -------------------------PIGPS----------------------------------- 201

  Fly   515 IFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVN 579
                  ||..|
 Frog   202 ------TTDKI------------------------------------------------------ 206

  Fly   580 SELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHR 644
                                 .|||:                  :|:           |...|:.
 Frog   207 ---------------------QKKPA------------------QDL-----------AEKGTNE 221

  Fly   645 YRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFII 709
            ..|.|:..|..|...|       |:|..:..:.....:.|.:||....|.::.:..:.:|..|..
 Frog   222 TLLTANKLPPSYGTKM-------EETKQETCLQKFNKVLDLTLFKHRGFMIYLVGNVVMFFAFYA 279

  Fly   710 PYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICY---------SLCM 765
            |.::|..|.|....|...:|.|:|.:.|.......|.|.:.:..|:...|.|         ..|.
 Frog   280 PIVFLTPYAKHLGVDEYSAAFLLSILAIVDMFARPGTGLIANTKWVRPKIQYFFSFSVTFNGFCH 344

  Fly   766 LVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVG 830
            |:|.        ..|.|:||:|..|.||..|....:.....|:.:|.:..|:.|.|||.:|:.|.
 Frog   345 LMCP--------FATGYVGLVVYSVFFGLAFGMVCALLFETLMDLVGVKRFSSAVGLVTIVECVP 401

  Fly   831 MIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFCE----KKAPKESDSDVLETKKA 890
            ::.||||.|.|.:..|.:...::..|..:.|:|:..:::.:..    :|..||..:..:|.|::
 Frog   402 LLLGPPIGGAIVDAFGDYKYMYFECGAIMVLAGLFLFVMNYYNYRMLEKEEKEKQAKEMEMKES 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	63/175 (36%)
		MFS	<685..869	CDD:119392	50/192 (26%)
LOC100491288	XP_031757084.1	2A0113	10..448	CDD:273325	143/760 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm14090
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010