Protein Alignment Rab2 and RAB9A

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 69/213 - (32%)
• Similarity: 110/213 - (51%)
• Gaps: 23/213 - (10%)

  Fly     6 LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRS 70
            |||.|::||.|||||.|:.::...:|......||||||..:.:.:||..:.:|||||||||.|||
Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71

  Fly    71 ITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSN----SNMVIMLIGNKSDLDSRREVKK 131
            :...:|||:...||.:.:...::|.:|:.|.::...:::    .:...:::|||.|: |.|:|..
Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDI-SERQVST 135

  Fly   132 EEGEAFAREHG-LVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTN 195
            ||.:|:.|::| ..:.||||:.|.||..||....:.:..........|..:...:     |....
Human   136 EEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQTDTVNL-----HRKPK 195

  Fly   196 PSLPGAGGAAGAANSGCC 213
            ||            |.||
Human   196 PS------------SSCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	67/211 (32%)
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	62/165 (38%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		3/10 (30%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		7/13 (54%)