Protein Alignment Rab2 and RAB2B

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_116235.2
• Gene: RAB2B / 84932
• HGNCID: 20246
• Length: 216
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 180/216 - (83%)
• Similarity: 195/216 - (90%)
• Gaps: 3/216 - (1%)

  Fly     1 MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQ 65
            |:|||||||||||||||||||||||||||||||||||||||||||||:.||||||||||||||||
Human     1 MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQ 65

  Fly    66 EAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVK 130
            |:|||||||||||||||||||||||||||||||:|||||||||:||||||||||||||:|||:||
Human    66 ESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVK 130

  Fly   131 KEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHS--- 192
            :||||||||||||:||||||:||.||||||||||||||.|||:|:||::|||||||||.|.|
Human   131 REEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSIST 195

  Fly   193 PTNPSLPGAGGAAGAANSGCC 213
            ...||..........:|||||
Human   196 SVGPSASQRNSRDIGSNSGCC 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	178/214 (83%)
RAB2B	NP_116235.2	PLN03108	1..216	CDD:178655	178/214 (83%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		4/4 (100%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		7/8 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..216		7/26 (27%)