Protein Alignment Rab2 and RAB6C

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_115520.2
• Gene: RAB6C / 84084
• HGNCID: 16525
• Length: 254
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 66/208 - (31%)
• Similarity: 110/208 - (52%)
• Gaps: 17/208 - (8%)

  Fly     7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSI 71
            ||.:.:|:..|.|:.|:.:|....|...:...||::|.::.:.::...|.|::|||||||..||:
Human    14 FKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSL 78

  Fly    72 TRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEA 136
            ...|.|.:|.|::|||||...:|...|.|::|.|....|:::|.|:||::||..:|:|..||||.
Human    79 IPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIITLVGNRTDLADKRQVSVEEGER 143

  Fly   137 FAREHGLVFMETSARTAANVEEAFINTAKEI--YEKIQEGVFDINNEANGIKIGQQHSPTNPSLP 199
            .|:...:.|:||.|:...||::.|...|..:  .|..|:|   ...:.:.||:.:....|
Human   144 KAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDG---SREDMSDIKLEKPQEQT----- 200

  Fly   200 GAGGAAGAANSGC 212
                   .:..||
Human   201 -------VSEGGC 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	66/208 (32%)
RAB6C	NP_115520.2	Required for centrosome localization	1..174		58/159 (36%)
		Rab6	14..174	CDD:206654	58/159 (36%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20340	32..50		4/17 (24%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20340	69..88		9/18 (50%)