Protein Alignment Rab2 and Rab1b

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_083852.1
• Gene: Rab1b / 76308
• MGIID: 1923558
• Length: 201
• Species: Mus musculus
• Alignment Length: 211
• Identity: 95/211 - (45%)
• Similarity: 136/211 - (64%)
• Gaps: 14/211 - (6%)

  Fly     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEA 67
            |.||||.::|||:|||||||||:|.|..:...:..||||:|..|.|.:|||.||||||||||||.
Mouse     5 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69

  Fly    68 FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKE 132
            ||:||.||||||.|.::|||:|.:|::.::..||::..::::.|:..:|:||||||.:::.|...
Mouse    70 FRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNT 134

  Fly   133 EGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPS 197
            ..:.||...|:.|:||||:.|.|||:||:..|.||.:::..|... ..|...:||  ..:|..|
Mouse   135 TAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAAS-GGERPNLKI--DSTPVKP- 195

  Fly   198 LPGAGGAAGAANSGCC 213
                      |:.|||
Mouse   196 ----------ASGGCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	93/209 (44%)
Rab1b	NP_083852.1	Rab1_Ypt1	7..172	CDD:206661	84/164 (51%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	30..45		5/14 (36%)
		Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250|UniProtKB:Q9H0U4	64..83		15/18 (83%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	65..80		11/14 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201		8/40 (20%)