Protein Alignment Rab2 and Rab25

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_058595.2
• Gene: Rab25 / 53868
• MGIID: 1858203
• Length: 213
• Species: Mus musculus
• Alignment Length: 219
• Identity: 91/219 - (41%)
• Similarity: 128/219 - (58%)
• Gaps: 25/219 - (11%)

  Fly     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHD--LTIGVEFGARMITIDGKQIKLQIWDTAGQ 65
            |.::||.::||::||||:.||.:||...|.  ||  .||||||..|.:.:....:|.|||||||.
Mouse     9 YNFVFKVVLIGESGVGKTNLLSRFTRNEFS--HDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGL 71

  Fly    66 EAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVK 130
            |.:|:||.:|||||.|||||:|:|:.:|:..:..||::...|:.:.:|:||:||||||...|||.
Mouse    72 ERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVP 136

  Fly   131 KEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTN 195
            .||...||..:||:|:||||..:.|||.||....|||:.|:.:               |:.:.|.
Mouse   137 TEEACMFAENNGLLFLETSALDSTNVELAFQTVLKEIFAKVSK---------------QKQNSTR 186

  Fly   196 PSLPGAGGAAGAANSG------CC 213
            .|....|.|....:.|      ||
Mouse   187 TSAITLGNAQAGQDPGPGEKRACC 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	89/217 (41%)
Rab25	NP_058595.2	Rab11_like	11..174	CDD:206660	80/164 (49%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	35..49		7/15 (47%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	67..84		10/16 (63%)