Protein Alignment Rab2 and RAB6B

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_057661.3
• Gene: RAB6B / 51560
• HGNCID: 14902
• Length: 208
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 75/212 - (35%)
• Similarity: 123/212 - (58%)
• Gaps: 25/212 - (11%)

  Fly     7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSI 71
            ||.:.:|:..|||:.|:.:|....|...:..|||::|.::.:.::.:.::||:|||||||.|||:
Human    14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSL 78

  Fly    72 TRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEA 136
            ..||.|.:..|::|||||...:|...:.|::|.|....|:::|||:|||:||..:|::..||||.
Human    79 IPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQ 143

  Fly   137 FAREHGLVFMETSARTAANVEEAFINTA------KEIYEKIQEGVFDINNEANGIKIGQQHSPTN 195
            .|:|..::|:||||:|..||::.|...|      :.:.||.:||:.|       ||:.:...|.
Human   144 RAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMID-------IKLDKPQEPP- 200

  Fly   196 PSLPGAGGAAGAANSGC 212
                       |:..||
Human   201 -----------ASEGGC 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	75/212 (35%)
RAB6B	NP_057661.3	Rab6	14..174	CDD:206654	64/159 (40%)
		Switch 1. /evidence=ECO:0000269|PubMed:16790928, ECO:0007744|PDB:2FE4, ECO:0007744|PDB:2FFQ	39..49		3/9 (33%)
		Switch 2. /evidence=ECO:0000269|PubMed:16790928, ECO:0007744|PDB:2FE4, ECO:0007744|PDB:2FFQ	71..87		9/15 (60%)