Protein Alignment Rab2 and RAB19

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001008749.2
• Gene: RAB19 / 401409
• HGNCID: 19982
• Length: 217
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 85/204 - (41%)
• Similarity: 128/204 - (62%)
• Gaps: 11/204 - (5%)

  Fly     2 SYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQE 66
            ::.||||.|:|||:.|||:|::..|....:......||||:|..|.:.||||::|:|:|||||||
Human    13 NFDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQVWDTAGQE 77

  Fly    67 AFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKK 131
            .||:||:||||.|..|::.||:|||.||..:..|:.:..::..:|:||||||||.||..:|.|..
Human    78 RFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIGNKCDLWEKRHVLF 142

  Fly   132 EEGEAFAREHGLV-FMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEA--NGIKIGQQHSP 193
            |:....|.::||: .:||||:.:.|:||.|:..|||:   |......:..|:  ||:.:     .
Human   143 EDACTLAEKYGLLAVLETSAKESKNIEEVFVLMAKEL---IARNSLHLYGESALNGLPL-----D 199

  Fly   194 TNPSLPGAG 202
            ::|.|...|
Human   200 SSPVLMAQG 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	85/204 (42%)
RAB19	NP_001008749.2	Rab19	15..179	CDD:133267	77/163 (47%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	39..54		4/14 (29%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	74..89		11/14 (79%)