Protein Alignment Rab2 and RAB43

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_940892.1
• Gene: RAB43 / 339122
• HGNCID: 19983
• Length: 212
• Species: Homo sapiens
• Alignment Length: 166
• Identity: 82/166 - (49%)
• Similarity: 116/166 - (69%)
• Gaps: 1/166 - (0%)

  Fly     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEA 67
            |.:|||.:::||..|||:|::.:|....|......||||:|..:.:.|.||::|||||||||||.
Human    15 YDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQER 79

  Fly    68 FRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKE 132
            ||:||:||||.|.||:|.||||:|.:|..:..|:||.|:::.||:|.:||||||||...|||...
Human    80 FRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSELREVSLA 144

  Fly   133 EGEAFAREHG-LVFMETSARTAANVEEAFINTAKEI 167
            |.::.|..:. |..:||||:.::||||||:..|.|:
Human   145 EAQSLAEHYDILCAIETSAKDSSNVEEAFLRVATEL 180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	82/166 (49%)
RAB43	NP_940892.1	Rab19	16..180	CDD:133267	80/163 (49%)
		Effector region. /evidence=ECO:0000250	47..55		4/7 (57%)