Protein Alignment Rab2 and RAB7B

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_796377.3
• Gene: RAB7B / 338382
• HGNCID: 30513
• Length: 199
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 69/212 - (32%)
• Similarity: 105/212 - (49%)
• Gaps: 28/212 - (13%)

  Fly     8 KYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSIT 72
            |.||:|..||||:.||.|:..|.|...:..|:|....:::|.:....:|||||||.|||.|||:.
Human    10 KLIIVGAIGVGKTSLLHQYVHKTFYEEYQTTLGASILSKIIILGDTTLKLQIWDTGGQERFRSMV 74

  Fly    73 RSYYRGAAGALLVYDITRRETFNHLTTWLEDARQH---SNSNMVIMLIGNKSDLDSRREVKKEEG 134
            .::|:|:.|.:|.:|:|..|:|..|..|..|....   ...:..::|:|||.|| :.|:|.:|..
Human    75 STFYKGSDGCILAFDVTDLESFEALDIWRGDVLAKIVPMEQSYPMVLLGNKIDL-ADRKVPQEVA 138

  Fly   135 EAFAREHGLVFMETSARTAANVEEAF---INTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNP 196
            :.:.||..:.:.|.||:...||.:||   .:.|...|:.|.|     |:....||:....|
Human   139 QGWCREKDIPYFEVSAKNDINVVQAFEMLASRALSRYQSILE-----NHLTESIKLSPDQS---- 194

  Fly   197 SLPGAGGAAGAANSGCC 213
                        .|.||
Human   195 ------------RSRCC 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	67/210 (32%)
RAB7B	NP_796377.3	Rab	9..169	CDD:206640	58/159 (36%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P51149	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P51149	67..82		7/14 (50%)