DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab2 and RAB37

DIOPT Version :10

Sequence 1:NP_477090.1 Gene:Rab2 / 35577 FlyBaseID:FBgn0014009 Length:213 Species:Drosophila melanogaster
Sequence 2:NP_001006639.1 Gene:RAB37 / 326624 HGNCID:30268 Length:223 Species:Homo sapiens


Alignment Length:167 Identity:81/167 - (48%)
Similarity:121/167 - (72%) Gaps:1/167 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SYAYLFKYIIIGDTGVGKSCLLLQFTDKRF-QPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQ 65
            ||....|.:::|||||||:|.|:||.|..| ......|:|::|..:::|:||.::||||||||||
Human    25 SYDLTGKVMLLGDTGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQ 89

  Fly    66 EAFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVK 130
            |.|||:|.:|||.|...||:||||.:.:|:::..||.:..:::..::||||:|||:|:.|.|.::
Human    90 ERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADMSSERVIR 154

  Fly   131 KEEGEAFAREHGLVFMETSARTAANVEEAFINTAKEI 167
            .|:||..|||:|:.|:||||:|..|||.||:..|||:
Human   155 SEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKEL 191

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab2NP_477090.1 PLN03108 1..213 CDD:178655 81/167 (49%)
RAB37NP_001006639.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
Rab26 31..220 CDD:206695 79/161 (49%)
Switch 1. /evidence=ECO:0000250|UniProtKB:P62820 52..67 3/14 (21%)
Switch 2. /evidence=ECO:0000250|UniProtKB:P62820 85..102 12/16 (75%)
Blue background indicates that the domain is not in the aligned region.

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