Protein Alignment Rab2 and RAB12

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001020471.3
• Gene: RAB12 / 201475
• HGNCID: 31332
• Length: 340
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 81/198 - (40%)
• Similarity: 124/198 - (62%)
• Gaps: 6/198 - (3%)

  Fly     5 YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFR 69
            :..:.||||..||||:.|:.:|||..|......|:||:|..:.:.:.||:|:||||||||||.|.
Human   137 FKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFN 201

  Fly    70 SITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEG 134
            |||.:|||.|.|.:||||||::|||:.|..|::...::::.:..::|:|||.|.::.||:.:::|
Human   202 SITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQG 266

  Fly   135 EAFARE-HGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDI--NNEANGIKIGQQHSPTNP 196
            |.||:: .|:.|.|.||:...||:|.|:....:|.:|:.   .||  |..:|.|...|......|
Human   267 EKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMP---LDILRNELSNSILSLQPEPEIPP 328

  Fly   197 SLP 199
            .||
Human   329 ELP 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	81/198 (41%)
RAB12	NP_001020471.3	Rab12	139..340	CDD:206699	81/196 (41%)