Protein Alignment Rab2 and Rab5b

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_803130.1
• Gene: Rab5b / 19344
• MGIID: 105938
• Length: 215
• Species: Mus musculus
• Alignment Length: 219
• Identity: 80/219 - (36%)
• Similarity: 124/219 - (56%)
• Gaps: 38/219 - (17%)

  Fly     7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSI 71
            ||.:::|::.||||.|:|:|...:|....:.|||..|..:.:.:|...:|.:||||||||.:.|:
Mouse    21 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 85

  Fly    72 TRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEA 136
            ...|||||..|::|||||.:|||....||:::.::.::.::||.|.|||:||.::|.|:.||.:|
Mouse    86 APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQA 150

  Fly   137 FAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPSLPGA 201
            :|.::.|:||||||:||.||.:.|:..||::                     .:..|.|     .
Mouse   151 YADDNSLLFMETSAKTAMNVNDLFLAIAKKL---------------------PKSEPQN-----L 189

  Fly   202 GGAAGAA------------NSGCC 213
            |||||.:            .|.||
Mouse   190 GGAAGRSRGVDLHEQSQQNKSQCC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	78/217 (36%)
Rab5b	NP_803130.1	Rab5_related	20..182	CDD:206653	70/181 (39%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	44..56		4/11 (36%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	77..93		8/15 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..215		10/33 (30%)