DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mob4 and MOB1

DIOPT Version :9

Sequence 1:	NP_001246151.1	Gene:	Mob4 / 35576	FlyBaseID:	FBgn0259483	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_012160.2	Gene:	MOB1 / 854700	SGDID:	S000001368	Length:	314	Species:	Saccharomyces cerevisiae

Alignment Length:	238	Identity:	59/238 - (24%)
Similarity:	105/238 - (44%)	Gaps:	35/238 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KMADGSTILRRNRPGTKS----KDFCRWP--DEPL--EEMDSTLAVQQYIQQLIKRDPSNVELI- 57
            :|:...|..:|:.|..:.    .||...|  .:|.  .:..:|:...|.|:|:::....:..::
Yeast    78 RMSPVLTTPKRHAPPPEQLQNVTDFNYTPSHQKPFLQPQAGTTVTTHQDIKQIVEMTLGSEGVLN 142

  Fly    58 --LTMPEAQDEGVWKYEHLRQFCMELNGLAVRLQKECSPSTCTQMTATDQWIFLCAAHK--TPKE 118
              :.:|..:||..|...|...|..::|.|...:.:.|||.||.:|.||:::.:|.|..|  .|..
Yeast   143 QAVKLPRGEDENEWLAVHCVDFYNQINMLYGSITEFCSPQTCPRMIATNEYEYLWAFQKGQPPVS 207

  Fly   119 CPAIDYTRHTLDGAACLL-------NSNKYFPSSVSPRVSIKESSVTK-LGSVCRRVYRIFSHAY 175
            ..|..|..       ||:       :....|||.|:.  :..|..:.: :..:.||::|:::|.|
Yeast   208 VSAPKYVE-------CLMRWCQDQFDDESLFPSKVTG--TFPEGFIQRVIQPILRRLFRVYAHIY 263

  Fly   176 FHHRRIFDEFEAETYLCHRFTHFVTKYNLMSKE-NLIVPINVG 217
            .||.....|...:|.|...|.||.    |.::| .|:.|.:.|
Yeast   264 CHHFNEILELNLQTVLNTSFRHFC----LFAQEFELLRPADFG 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mob4	NP_001246151.1	Mob1_phocein	53..211	CDD:397617	44/171 (26%)
MOB1	NP_012160.2	Mob1_phocein	134..304	CDD:397617	47/182 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910