Protein Alignment Tdc1 and CSAD

DIOPT Version :9

• Sequence 1: NP_610226.2
• Gene: Tdc1 / 35573
• FlyBaseID: FBgn0259977
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_024304779.1
• Gene: CSAD / 51380
• HGNCID: 18966
• Length: 620
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 114/447 - (25%)
• Similarity: 185/447 - (41%)
• Gaps: 79/447 - (17%)

  Fly    13 VIDYICQYGTNIEERDVAPTLDPGYLKKLLPADAPQSPEPFKDVLEDFEQKIMPGVVHWNHPKFF 77
            |:|...|.||::.:: |....:|..||:||..:.....|..|.:||.. :.::...|...||:||
Human   124 VVDEAIQKGTSVSQK-VCEWKEPEELKQLLDLELRSQGESQKQILERC-RAVIRYSVKTGHPRFF 186

  Fly    78 AYFPSGNSFPSVLGDMLSSAIGSIGFSWASCPAAAELETIVMNWYAKALGLPKAFVSDAPGSTGG 142
            ....||....::.|.:::.::.:..:::...|....:|..|:......:|          .|:|.
Human   187 NQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVG----------WSSGD 241

  Fly   143 GAL--QGSASECVLVSLITARARAISELKGQTSVHDSVFLPSLIAYASRE--------------- 190
            |..  .||.|....|:|  ||.:...:.| |..:..   ||.|..:.|:|
Human   242 GIFCPGGSISNMYAVNL--ARYQRYPDCK-QRGLRT---LPPLALFTSKEVGKRHRPNPGLLILI 300

  Fly   191 -AHSSVEKATKMALVKL--------RIIDADE------HGRM---RVDLLRQAIQNDV-NAGLTP 236
             :|.:.....::....|        |::...:      .||:   |:.|.....:..: ::|..|
Human   301 SSHVTTPSRRELRFWDLAPTVSEWSRLMREGKWSPRIWRGRLVWPRLRLTFHFFETFILDSGAVP 365

  Fly   237 FFVVATVGTTGGCAFDDITEIGKVCRQVSSIWLHVDGAYAGNSFILPEMRVFSAGLEYADSFNTN 301
            |.|.||.|||...|||.:..|..|| |...:|||||.|:.|:..:....|....|::.|||...|
Human   366 FLVSATSGTTVLGAFDPLEAIADVC-QRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAWN 429

  Fly   302 PNKLLLTNFDASALWVRDVMNLKSALNVNPLYLRHEHLTGVDY-----RHYGIPL---------S 352
            |:|||......|||.::|..||          |:..|.:...|     :.|.:.|         .
Human   430 PHKLLAAGLQCSALLLQDTSNL----------LKRCHGSQASYLFQQDKFYDVALDTGDKVVQCG 484

  Fly   353 RRFRALKLWFVFRTYGIRGLQEYIRNHMALAKKFEMLVRKDERFEVRNDVHLGLVCF 409
            ||...||||.:::..|.:||:..|.....||:.....::|.|.||:..:.....|||
Human   485 RRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCF 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc1	NP_610226.2	Pyridoxal_deC	35..412	CDD:278699	108/425 (25%)
CSAD	XP_024304779.1	DOPA_deC_like	185..616	CDD:99743	96/384 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810