Protein Alignment Tdc1 and SEPSECS

DIOPT Version :9

• Sequence 1: NP_610226.2
• Gene: Tdc1 / 35573
• FlyBaseID: FBgn0259977
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_016863766.1
• Gene: SEPSECS / 51091
• HGNCID: 30605
• Length: 586
• Species: Homo sapiens
• Alignment Length: 515
• Identity: 104/515 - (20%)
• Similarity: 169/515 - (32%)
• Gaps: 182/515 - (35%)

  Fly   154 LVSLITARARAIS---ELKGQTSVHDSVFLPSLIAYASREAHSSVEKA---------TKMALVKL 206
            |:.|:..::.|:|   |.....|.|.|:.||     .||.:.:|..:.         |::..|.|
Human    31 LIRLLLEKSLALSPRLECSVTISAHCSLRLP-----GSRHSPASASRVAGTTGARHHTRLMFVFL 90

  Fly   207 RIIDADEHGRMRVDLLRQAIQNDVNAGLTPFFVVATVGTTGG-C---AFDDITEIGKVCRQVSSI 267
            ..:.....|:..:.||..:.:        ||....:...||| |   .:|:.|         ..:
Human    91 VEMGFHHVGQADLKLLTSSDR--------PFLAFQSARITGGKCPENGWDEST---------LEL 138

  Fly   268 WLHVDGAYAGNSFI------LPEMRVFSA-----------GLEYADSFNTNPNKLLLTNFDASAL 315
            :||.......|:|:      ..|.||.||           |:..:.              |.||
Human   139 FLHELAIMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSG--------------DISA- 188

  Fly   316 WVRDVMNLKSALN--VNPLYLRHEHLTGVDYRH-----YGIPLSRRFRALKLWFVFRTYGIRGLQ 373
             |:......|.||  .|.|.|....|.||   |     :.:|::   ..:.|...|.|
Human   189 -VQPKAAGSSLLNKITNSLVLDIIKLAGV---HTVANCFVVPMA---TGMSLTLCFLT------- 239

  Fly   374 EYIRNHMALAK-------------------KFEMLVRKD--ERFEVRND---------------- 401
              :|:....||                   .||.:|.::  |..|:|.|
Human   240 --LRHKRPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCI 302

  Fly   402 --VHLGLVCFRMRTGDEPNHMLLAQINHSGKMHMTPAKFNGRYVIRF--CVTYEHATEKDI---- 458
              :|....||..|..|....:.:...|:.     .|...|..|.::.  |:   |..::..
Human   303 LCIHSTTSCFAPRVPDRLEELAVICANYD-----IPHIVNNAYGVQSSKCM---HLIQQGARVGR 359

  Fly   459 LEAWTQ--------------IKCFAEEILRDHQLESSSVPTTPEGSERTSSEPLAPV------AG 503
            ::|:.|              |..|.:..:::   .|...|      .|.|:.|...|      .|
Human   360 IDAFVQSLDKNFMVPVGGAIIAGFNDSFIQE---ISKMYP------GRASASPSLDVLITLLSLG 415

  Fly   504 KPPIKKRLTRTKSLRFSFTRSISREQYQSQSEHLMDGCTP----ILVVDPKTLQENFQKA 559
            ....||.|...|.: ||:..:..::..::.:|.|:.  ||    .|.:..|||.|:..||
Human   416 SNGYKKLLKERKEM-FSYLSNQIKKLSEAYNERLLH--TPHNPISLAMTLKTLDEHRDKA 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc1	NP_610226.2	Pyridoxal_deC	35..412	CDD:278699	68/336 (20%)
SEPSECS	XP_016863766.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900