Protein Alignment Tdc1 and tdc-1

DIOPT Version :9

• Sequence 1: NP_610226.2
• Gene: Tdc1 / 35573
• FlyBaseID: FBgn0259977
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_495743.1
• Gene: tdc-1 / 174327
• WormBaseID: WBGene00006562
• Length: 705
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 279/546 - (51%)
• Similarity: 368/546 - (67%)
• Gaps: 17/546 - (3%)

  Fly     1 MDVEEFRKYGKEVIDYICQYGTNIEERDVAPTLDPGYLKKLLPADAPQSPEPFKDVLEDFEQKIM 65
            |..:|||:||||.:|||..|..||::|.|.|.::|||||.|:|::||.:||.|:.|:||||:.||
 Worm    77 MTRDEFRQYGKETVDYIVDYLENIQKRRVVPAIEPGYLKDLIPSEAPNTPESFESVMEDFEKLIM 141

  Fly    66 PGVVHWNHPKFFAYFPSGNSFPSVLGDMLSSAIGSIGFSWASCPAAAELETIVMNWYAKALGLPK 130
            ||:.||.||:|.||||:||||||::.||||.|||.:|||||:|||..|||.|:::|:.|.:|||.
 Worm   142 PGITHWQHPRFHAYFPAGNSFPSIIADMLSDAIGCVGFSWAACPAMTELELIMLDWFGKMIGLPA 206

  Fly   131 AFVSDAPGSTGGGALQGSASECVLVSLITARARAISELKGQ-TSVHDSVFLPSLIAYASREAHSS 194
            .|:.......|||.:|.|||||..|:|:.||...:.||:.: ..|.:.:.|..||||.|:|||||
 Worm   207 EFLPLTENGKGGGVIQSSASECNFVTLLAARFEVMKELRQRFPFVEEGLLLSKLIAYCSKEAHSS 271

  Fly   195 VEKATKMALVKLRIIDADEHGRMRVDLLRQAIQNDVNAGLTPFFVVATVGTTGGCAFDDITEIGK 259
            ||||..:.:|||||::.|...|:|.|.||.|||.|.|.||.||||..|:|||..|:||.::|||.
 Worm   272 VEKACMIGMVKLRILETDSKFRLRGDTLRNAIQEDRNLGLIPFFVSTTLGTTSCCSFDVLSEIGP 336

  Fly   260 VCRQVSSIWLHVDGAYAGNSFILPEMRVFSAGLEYADSFNTNPNKLLLTNFDASALWVRDVMNLK 324
            :|:: :.:|||||.||:|::||.||.|....|:|||.||||||||.||.|||.|.:||||...|.
 Worm   337 ICKE-NELWLHVDAAYSGSAFICPEFRPLMNGIEYAMSFNTNPNKWLLINFDCSTMWVRDRFKLT 400

  Fly   325 SALNVNPLYLRHEHL-TGVDYRHYGIPLSRRFRALKLWFVFRTYGIRGLQEYIRNHMALAKKFEM 388
            .||.|:||||:|..: ..:||||:|||||||||:||||||.|.|||.|||:|||.|:.||||.|.
 Worm   401 QALVVDPLYLQHSWMDKSIDYRHWGIPLSRRFRSLKLWFVIRMYGIDGLQKYIREHVRLAKKMET 465

  Fly   389 LVRKDERFEVRNDVHLGLVCFRMRTGDEPNHMLLAQINHSGKMHMTPAKFNGRYVIRFCVTYEHA 453
            |:|.|.:||:.|:|.:|||||||:..||.|..||.::|.||::||.||....|:||||||..|:|
 Worm   466 LLRADAKFEIVNEVIMGLVCFRMKGDDELNQTLLTRLNASGRIHMVPASLGDRFVIRFCVCAENA 530

  Fly   454 TEKDILEAWTQIKCFAEEILRDHQLESSSVPTTPEGSERTSSEPLAP---VAGKPPIKKRLTRTK 515
            |:|||..|:..|....:.:|.|    |.......|..|..:.|.:..   :...|  :|.|||..
 Worm   531 TDKDIEVAYEIIAQATQHVLHD----SVKAVIAEEDEEAVALEEMVADLNITETP--EKCLTRQN 589

  Fly   516 SLRFS-----FTRSISREQYQSQSEH 536
            |...:     ..|.:|:|:..:|.:|
 Worm   590 SANAAESGQKLERQLSKEEILAQKQH 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc1	NP_610226.2	Pyridoxal_deC	35..412	CDD:278699	217/378 (57%)
tdc-1	NP_495743.1	Pyridoxal_deC	111..489	CDD:278699	217/378 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.815392	Normalized mean entropy	S2516
OMA	1	1.010	-	-		QHG57772
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100572
Panther	1	1.100	-	-	O	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X696
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.880