Protein Alignment Tdc1 and gad1.2

DIOPT Version :10

• Sequence 1: NP_610226.2
• Gene: Tdc1 / 35573
• FlyBaseID: FBgn0259977
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_012819752.1
• Gene: gad1.2 / 100145511
• XenbaseID: XB-GENE-5830282
• Length: 554
• Species: Xenopus tropicalis
• Alignment Length: 451
• Identity: 110/451 - (24%)
• Similarity: 182/451 - (40%)
• Gaps: 83/451 - (18%)

  Fly    16 YICQYGTNIEERDVAPT--------------------------------LDPGYLKKLLPA---- 44
            ||..: :||...|:.||                                ||..:..:||..
 Frog    51 YISDF-SNIYSTDLLPTRNGEKCTEQFLIEVLRILLNHIKKTYDGESKVLDFHHPHQLLEGLEGF 114

  Fly    45 --DAPQSPEPFKDVLEDFEQKIMPGVVHWNHPKFFAYFPSGNSFPSVLGDMLSSAIGSIGFSWAS 107
              :....|||.:.:|.|....:... :...||::|.....|.....:.|:.|::...:..|::..
 Frog   115 NLELSDQPEPLEQILVDCSDTLKYS-IKTGHPRYFNQLSCGLDIIGLAGEWLTATANTNMFTYEI 178

  Fly   108 CPAAAELETIVMNWYAKALGLPKAFVSDAPGSTGGGALQGSASECVLVSLITARAR--AISELKG 170
            .|....:|.||:....:.:|..:   ::|.|....|   |:.|.  |.||..||.:  .:.:.||
 Frog   179 APVFIIMEEIVLKKMQEIIGWGE---NEADGIFSPG---GTISN--LYSLQAARYKYFPMVKTKG 235

  Fly   171 QTSVHDSVFLPSLIAYASREAHSSVEKATKMALV---KLRIIDADEHGRMRVDLLRQAIQNDVNA 232
            ..:      ||.::.:.|.::|.|.:||:.:..:   .:..|..||.|:|....|...|......
 Frog   236 MAA------LPQIVIFTSEQSHYSFKKASAILGIGTDNVIAIKCDERGKMIPSDLEDKILKAKRQ 294

  Fly   233 GLTPFFVVATVGTTGGCAFDDITEIGKVCRQVSSIWLHVDGAYAGNSFILPEMRVFSAGLEYADS 297
            |..||:|.||.|||...|||.:..|..:|::. .:|:|||.|:.|...:..:.|....|:|.|:|
 Frog   295 GQHPFYVSATAGTTVYGAFDPLITIADICKRY-GLWMHVDAAWGGGLLLSKKHRYKMNGIERANS 358

  Fly   298 FNTNPNKLLLTNFDASALWVRDVMNLKSALN---VNPLY-LRHEHLTGVDYRHYGIPLSRRFRAL 358
            ...||:|::......||:.:|. ..|..|.|   .:.|: :...:.|..|.....|...|.....
 Frog   359 VTWNPHKIMGVPLQCSAILIRQ-KGLLQACNQQCADYLFQMDKPYDTAYDTGDKTIQCGRHVDIF 422

  Fly   359 KLWFVFRTYGIRG----------LQEYIRNHMALAKKFEMLVRKDERFEVRNDVHLGLVCF 409
            |||.:::..|..|          |.||:.|.:.....||::.|  ::.|..|      |||
 Frog   423 KLWLMWKAKGSCGFELQINRCLELSEYLYNKLQSKSNFELVFR--DKPEYTN------VCF 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdc1	NP_610226.2	Pyridoxal_deC	35..412	CDD:395219	101/400 (25%)
gad1.2	XP_012819752.1	Pyridoxal_deC	104..478	CDD:395219	101/397 (25%)