DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17266 and Ppid

DIOPT Version :9

Sequence 1:	NP_001246149.1	Gene:	CG17266 / 35571	FlyBaseID:	FBgn0033089	Length:	183	Species:	Drosophila melanogaster
Sequence 2:	NP_080628.1	Gene:	Ppid / 67738	MGIID:	1914988	Length:	370	Species:	Mus musculus

Alignment Length:	174	Identity:	97/174 - (55%)
Similarity:	117/174 - (67%)	Gaps:	4/174 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SSNNPVVFFDIAVGTTEIGRMIFELFADTVPRTAENFRQFCTGEY---RPDGVPIGYKGASFHRV 74
            :|.||.||||:.:|...:||::.|||||.||:||||||..||||.   ...|.|:.:||..|||:
Mouse    12 NSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGTGSTTGKPLHFKGCPFHRI 76

  Fly    75 IKDFMIQGGDFVQGDGTGVTSIYGNTFGDENFTLKHDSPGLLSMANSGKETNGCQFFITCAKCNF 139
            ||.||||||||...:|||..||||..|.||||..|||..|||||||:|..|||.|||||......
Mouse    77 IKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMANAGPNTNGSQFFITTVPTPH 141

  Fly   140 LDGKHVVFGRVLDGLLIMRKIENVPTGPNNKPKLPVTISQCGQM 183
            |||||||||:|:.||.:.|.:|||........||.| |::||::
Mouse   142 LDGKHVVFGQVIKGLGVARTLENVEVNGEKPAKLCV-IAECGEL 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17266	NP_001246149.1	cyclophilin_ABH_like	17..181	CDD:238907	93/166 (56%)
Ppid	NP_080628.1	cyclophilin_ABH_like	16..182	CDD:238907	93/166 (56%)
		Chaperone activity. /evidence=ECO:0000250	185..215		97/174 (56%)
		Interaction with HSP90AB1. /evidence=ECO:0000250	214..370
		TPR_11	223..304	CDD:290150
		TPR repeat	223..251	CDD:276809
		TPR repeat	272..302	CDD:276809
		TPR_11	277..338	CDD:290150
		TPR	277..306	CDD:197478
		TPR repeat	307..335	CDD:276809
		TPR_1	308..340	CDD:278916
		TPR repeat	341..364	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820