DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17266 and NKTR

DIOPT Version :9

Sequence 1:	NP_001246149.1	Gene:	CG17266 / 35571	FlyBaseID:	FBgn0033089	Length:	183	Species:	Drosophila melanogaster
Sequence 2:	NP_001336053.1	Gene:	NKTR / 4820	HGNCID:	7833	Length:	1463	Species:	Homo sapiens

Alignment Length:	172	Identity:	84/172 - (48%)
Similarity:	111/172 - (64%)	Gaps:	3/172 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SSNNPVVFFDIAVGTTEIGRMIFELFADTVPRTAENFRQFCTGEY---RPDGVPIGYKGASFHRV 74
            :.:.|...|||.:....:||::|:||:|..|:|.:||...|:||.   :..|..:.|||::||||
Human     3 AQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRV 67

  Fly    75 IKDFMIQGGDFVQGDGTGVTSIYGNTFGDENFTLKHDSPGLLSMANSGKETNGCQFFITCAKCNF 139
            :|:||||||||.:|:|.|..||||..|.||||.||||...||||||.||.|||.|||||......
Human    68 VKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPH 132

  Fly   140 LDGKHVVFGRVLDGLLIMRKIENVPTGPNNKPKLPVTISQCG 181
            |||.|||||.|:.|..::.:|||:.|...::|...|.:..||
Human   133 LDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCG 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17266	NP_001246149.1	cyclophilin_ABH_like	17..181	CDD:238907	82/166 (49%)
NKTR	NP_001336053.1	cyclophilin	7..174	CDD:320812	82/166 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..591
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	607..627
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	658..1072
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1129..1156
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1169..1215
		Arg/Ser tandem repeat-rich	1311..1348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820