DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17266 and CG8336

DIOPT Version :9

Sequence 1:	NP_001246149.1	Gene:	CG17266 / 35571	FlyBaseID:	FBgn0033089	Length:	183	Species:	Drosophila melanogaster
Sequence 2:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	83/173 - (47%)
Similarity:	111/173 - (64%)	Gaps:	4/173 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SNNPVVFFDIAVGTTEIGRMIFELFADTVPRTAENFRQFCTGE--YRPDGVPIGYKGASFHRVIK 76
            |.||:|:.||::|..:.||||.||..|.||:||||||..||||  ....|.|:.|||..||::.:
  Fly    12 STNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKR 76

  Fly    77 DFMIQGGDFVQGDGTGVTSIYGNTFGDENFTLKHDSPGLLSMANSGK-ETNGCQFFITCAKCNFL 140
            .|::|.||.|:.||:...||||..|.||||.|.|:..|::||||.|| .:|..||||:.|.|..|
  Fly    77 VFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENL 141

  Fly   141 DGKHVVFGRVLDGLLIMRKIENVPTGPNNKPKLPVTISQCGQM 183
            :|.:||.||||.||.|:.::|...|...: |..|:.|..||::
  Fly   142 NGTNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEI 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17266	NP_001246149.1	cyclophilin_ABH_like	17..181	CDD:238907	79/166 (48%)
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	79/166 (48%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447204
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850