DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17266 and CWC27

DIOPT Version :9

Sequence 1:	NP_001246149.1	Gene:	CG17266 / 35571	FlyBaseID:	FBgn0033089	Length:	183	Species:	Drosophila melanogaster
Sequence 2:	NP_005860.2	Gene:	CWC27 / 10283	HGNCID:	10664	Length:	472	Species:	Homo sapiens

Alignment Length:	155	Identity:	56/155 - (36%)
Similarity:	80/155 - (51%)	Gaps:	11/155 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 TEIGRMIFELFADTVPRTAENFRQFCTGEYRPDGVPIGYKGASFHRVIKDFMIQGGDFVQGDGTG 92
            |..|.:..||::...|:...||.|.|...|        |....||||:..|::|||| ..|.|:|
Human    19 TTAGDIDIELWSKEAPKACRNFIQLCLEAY--------YDNTIFHRVVPGFIVQGGD-PTGTGSG 74

  Fly    93 VTSIYGNTFGDE-NFTLKHDSPGLLSMANSGKETNGCQFFITCAKCNFLDGKHVVFGRVL-DGLL 155
            ..||||..|.|| :..|:.:..||::|||:|...||.|||.|..:.:.|:.||.:||:|. |.:.
Human    75 GESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHDNGSQFFFTLGRADELNNKHTIFGKVTGDTVY 139

  Fly   156 IMRKIENVPTGPNNKPKLPVTISQC 180
            .|.::..|....:.:|..|..|..|
Human   140 NMLRLSEVDIDDDERPHNPHKIKSC 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17266	NP_001246149.1	cyclophilin_ABH_like	17..181	CDD:238907	56/155 (36%)
CWC27	NP_005860.2	cyclophilin_CeCYP16-like	8..178	CDD:238906	56/155 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..386
		DUF5401	<302..>472	CDD:375164
		CWC27_CTD	376..428	CDD:412084
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	398..472
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810