DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGAP3 and PGAP3

DIOPT Version :9

Sequence 1:	NP_610223.1	Gene:	PGAP3 / 35570	FlyBaseID:	FBgn0033088	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_219487.3	Gene:	PGAP3 / 93210	HGNCID:	23719	Length:	320	Species:	Homo sapiens

Alignment Length:	314	Identity:	126/314 - (40%)
Similarity:	182/314 - (57%)	Gaps:	12/314 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IVLLLGALVTACLASNGDRTQFFHNCRQNCERTNCSADGLEIQEQAVKFYQQSVFDRLFQWSCAD 73
            :|||.||...|. .|.|||...:.:|...||..|||...|.....     :|.::..|..|:|.|
Human     8 LVLLAGAAALAS-GSQGDREPVYRDCVLQCEEQNCSGGALNHFRS-----RQPIYMSLAGWTCRD 66

  Fly    74 ECQYGCMWRTVFAFFERGWPIPQFYGKWPFLRLLGMQEPASVIFSCLNFVVHLRLLRKFRREVRP 138
            :|:|.|||.||..:.:.|..:|||:|||||.|.|..|||||.:.|.||.:..|.:|.::|..|..
Human    67 DCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLFFQEPASAVASFLNGLASLVMLCRYRTFVPA 131

  Fly   139 DSPCYMLTHIFAVTSLNGWIWSAIFHTRDFPLTELLDYAFAYSIILCSLYVMVMR---MLHRYSL 200
            .||.|.....||..|||.|.||.:|||||..|||.:||..|.::||.|:|:..:|   :.|...:
Human   132 SSPMYHTCVAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASTVILHSIYLCCVRTVGLQHPAVV 196

  Fly   201 FLRGVITLAFLSYYINYFAYLSVGRFNYAFNMMVNVATGVIAAVGWFVWCHFVRTRRPYFRRILR 265
            .....:.|..|:.::   :|||:.||:|.:|::.|||.|::..|.|..||.:.:.|.|:.|:.:.
Human   197 SAFRALLLLMLTVHV---SYLSLIRFDYGYNLVANVAIGLVNVVWWLAWCLWNQRRLPHVRKCVV 258

  Fly   266 FYILMALAMSLELLDFPPILWILDAHALWHLATIPLASLYYDFMIEDCRTLRKE 319
            ..:|:.....||||||||:.|:|||||:||::|||:..|::.|:.:|...|.||
Human   259 VVLLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKE 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGAP3	NP_610223.1	Per1	65..313	CDD:282000	104/250 (42%)
PGAP3	NP_219487.3	Per1	54..306	CDD:321836	104/254 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144507
Domainoid	1	1.000	213	1.000	Domainoid score	I2767
eggNOG	1	0.900	-	-		E1_COG5237
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5484
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3388
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59972
OrthoDB	1	1.010	-	-		D523376at33208
OrthoFinder	1	1.000	-	-		FOG0004451
OrthoInspector	1	1.000	-	-		oto90070
orthoMCL	1	0.900	-	-		OOG6_104144
Panther	1	1.100	-	-	LDO	PTHR13148
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R898
SonicParanoid	1	1.000	-	-		X3155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800